Abstract
Fish is a common cause of food allergy. The reactions usually occur after its ingestion. In most immunoglobulin E-mediated reactions, the allergens are gastroresistant and heat-stable proteins of low molecularweight (parvalbumin). On the other hand, isolated contact urticaria following the handling of raw fish but without symptoms after its ingestion was found among cooks and professional fish handlers. In these cases, the fish allergens are gastrosensitive and thermolabile, as demonstrated by the decrease in the diameter of the wheal in the skin-prick test using cooked fish. To the best of our knowledge isolated fish contact urticaria in children has not been previously reported. We analyze the features of three pediatric cases of contact urticaria from cod (one of them was sensitized to parvalbumin), with tolerance after ingestion of this fish on oral food challenge.
Links
Authors
Onesimo R, Giorgio V, Pill S, Monaco S, Sopo SM
Institution
Department of Pediatrics, Policlinico A. Gemelli, Catholic University, Rome, Italy. roberta_onesimo@yahoo.it
Source
The Israel Medical Association journal : IMAJ 14:1 2012 Jan pg 11-3MeSH
AnimalsChild
Child, Preschool
Dermatitis, Contact
Fishes
Food Hypersensitivity
Humans
Immunoglobulin E
Male
Parvalbumins
Skin Tests
Urticaria
Pub Type(s)
Case ReportsJournal Article
Language
eng
PubMed ID
22624435
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