Unbound MEDLINE

Isolated contact urticaria caused by immunoglobulin E-mediated fish allergy.

Abstract

Fish is a common cause of food allergy. The reactions usually occur after its ingestion. In most immunoglobulin E-mediated reactions, the allergens are gastroresistant and heat-stable proteins of low molecularweight (parvalbumin). On the other hand, isolated contact urticaria following the handling of raw fish but without symptoms after its ingestion was found among cooks and professional fish handlers. In these cases, the fish allergens are gastrosensitive and thermolabile, as demonstrated by the decrease in the diameter of the wheal in the skin-prick test using cooked fish. To the best of our knowledge isolated fish contact urticaria in children has not been previously reported. We analyze the features of three pediatric cases of contact urticaria from cod (one of them was sensitized to parvalbumin), with tolerance after ingestion of this fish on oral food challenge.

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  • Publisher Full Text
  • Authors

    Onesimo R, Giorgio V, Pill S, Monaco S, Sopo SM

    Institution

    Department of Pediatrics, Policlinico A. Gemelli, Catholic University, Rome, Italy. roberta_onesimo@yahoo.it

    Source

    The Israel Medical Association journal : IMAJ 14:1 2012 Jan pg 11-3

    MeSH

    Animals
    Child
    Child, Preschool
    Dermatitis, Contact
    Fishes
    Food Hypersensitivity
    Humans
    Immunoglobulin E
    Male
    Parvalbumins
    Skin Tests
    Urticaria

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    22624435