Abnormal bone metabolism in Crohn's disease.
Inflammatory bowel diseases (IBD) including Crohn's disease (CD) and ulcerative colitis (UC) have a major impact on the health of individuals and populations. These diseases result from an inappropriate immune response, in genetically susceptible individuals, to microbial antigens of commensal microorganisms. This paper reviews the abnormal bone metabolism associated with CD, in order to elucidate the mechanism of bone loss.
Institute of Digestive Disease, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
SourceFrontiers in bioscience : a journal and virtual library 17: 2012 pg 2675-83
MeSHAdrenal Cortex Hormones
Bone Diseases, Metabolic
Bone and Bones
Tumor Necrosis Factor-alpha
Vitamin D Deficiency
Pub Type(s)Journal Article
Research Support, Non-U.S. Gov't