Abstract

OBJECTIVES
To evaluate the feasibility and safety of a new unibody branched stent-graft for reconstruction of the canine aortic arch.
MATERIALS AND METHODS
Twenty adult hybrid dogs were used for the experiments. Ten dogs were implanted with single-branched stent-grafts; the other ten dogs were implanted with double-branched stent-grafts. The stent-grafts were implanted transluminally via the abdominal aorta. The branched limbs were caught and pulled into supra-aortic vessels using gooseneck snare wires introduced via the axillary arteries. The animals were euthanized 4 months after implantation.
RESULTS
One of the ten dogs implanted with a single-branched stent-graft died from failure of the implantation procedure, and two of the ten dogs implanted with double-branched stent-grafts died from failure of the procedure and excessive blood loss. After month 4, the remaining unibody branched stent-grafts were patent and did not migrate.
CONCLUSIONS
This new unibody branched stent-graft could be used to reconstruct the aortic arch. This is a total endovascular technique, and compared to other branched stent-grafts appears to be safer and easier to implant.

Links

Publisher Full Text

Authors

Li W, Xu K, Zhong H, Ni Y, Bi Y

Institution

Department of Radiology, The First Affiliated Hospital of China Medical University, Liaoning, People's Republic of China.

Source

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 44:2 2012 Aug pg 139-44

MeSH

Animals
Aorta, Thoracic
Aortography
Blood Vessel Prosthesis
Blood Vessel Prosthesis Implantation
Dogs
Endovascular Procedures
Feasibility Studies
Materials Testing
Models, Animal
Prosthesis Design
Prosthesis Failure
Stents
Time Factors
Tomography, X-Ray Computed

Pub Type(s)

Evaluation Studies
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22659046