Unbound MEDLINE

Constraint-induced movement therapy alters cerebral blood flow in subacute post-stroke patients.

Abstract

We attempted to evaluate patterns of hemispheric activation, according to cerebral blood flow changes, in post-stroke patients during motor tasks with and without arm restriction. Bilateral continuous middle cerebral artery monitoring of 6 healthy subjects (control group) and 28 post-stroke patients by transcranial Doppler sonography was executed while performing three simple motor tasks using the paretic or nondominant (in controls) hand: ball grasping, pegs insertion, and "eating" with a spoon. The nonaffected or dominant (in controls) arm was free and thereafter restricted. Mean blood flow velocity and flow velocity changes during the tests were estimated. No significant mean blood flow velocity changes were found in the healthy subjects. Significant elevation of mean blood flow velocity in damaged middle cerebral artery was recorded in post-stroke patients after restricting the undamaged hand. This may explain the positive effect of constraint-induced movement therapy on upper limb function.

Links

  • Publisher Full Text
  • Authors

    Treger I, Aidinof L, Lehrer H, Kalichman L

    Source

    American journal of physical medicine & rehabilitation / Association of Academic Physiatrists 91:9 2012 Sep pg 804-9

    MeSH

    Adult
    Aged
    Aged, 80 and over
    Arm
    Blood Flow Velocity
    Cerebrovascular Circulation
    Female
    Humans
    Male
    Middle Aged
    Middle Cerebral Artery
    Monitoring, Physiologic
    Movement
    Paresis
    Physical Therapy Modalities
    Stroke
    Ultrasonography, Doppler, Transcranial

    Pub Type(s)

    Controlled Clinical Trial
    Journal Article

    Language

    eng

    PubMed ID

    22660371