Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) emerged as a nosocomial pathogen in early 1960s, causing Increasing number of outbreaks in 19708, first reported in a teaching hospital in Malaysia in 1972, causing increased mortality, morbidity, and healthcare costs. Aim of this study is to screen out MRSA from various clinical samples and to see their antibiotic susceptibility pattern. From May 2008 to May 2009, 204 S aureus strains were isolated, out of which 114 (55.8%) were MRSA, and rest methicillin-sensitive Staphylococcus aureus (MSSA). Most of the MRSA strains were obtained from pus (45%) followed by urine (20.5%). Frequency of isolating MRSA were maximum in catheter tip (80%) followed by blood (66.7%) and pus (58.7%). MRSA strains were showing 100% sensitivity to vancomycin and Iinezolid, whereas 92.9% to teicoplanin. Therefore it is concluded that antibiotics other than vancomycin can be used as anti-MRSA agents after sensitivity test, as well as irrational and indiscriminate use of antibiotics can be avoided.

Authors

Tiwari S, Sahu M, Rautaraya B, Karuna T, Mishra SR, Bhattacharya S

Institution

Department of Microbiology, Hi-Tech Medical College Bhubaneswar 751025.

Source

Journal of the Indian Medical Association 109:11 2011 Nov pg 800-1

MeSH

Anti-Bacterial Agents
Blood
Catheters
Cross Infection
Humans
India
Methicillin-Resistant Staphylococcus aureus
Microbial Sensitivity Tests
Retrospective Studies
Staphylococcal Infections
Suppuration
Synovial Fluid
Urine

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22666934