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Unusual Merkel cell carcinoma of the eyelid.

Abstract

Merkel cell carcinoma of the eyelid is a rare tumor with less than 100 reported cases worldwide. We describe an unusual presentation of Merkel cell carcinoma of the eyelid in a 60 year old Asian male. He presented with multiple left lower lid conjunctival nodules, intense conjunctival erythema, as well as ipsilateral cervical lymphadenopathy. An incisional biopsy diagnosed him with Merkel cell carcinoma with a PET scan showing distant metastatic disease. He was then treated with chemotherapy. The combination of a presentation of conjunctival nodules and erythema, location in the lower eyelid and the conjunctiva, the presence of metastatic disease on diagnosis as well as an unusual immunohistochemical profile make this an unusual case.

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  • Publisher Full Text
  • Authors

    Shah JM, Sundar G, Tan KB, Zee YK

    Institution

    Department of Ophthalmology, National University of Singapore, Singapore.

    Source

    Orbit (Amsterdam, Netherlands) 31:6 2012 Dec pg 425-7

    MeSH

    Biopsy
    Carcinoma, Merkel Cell
    Diagnosis, Differential
    Disease Progression
    Eyelid Neoplasms
    Humans
    Immunohistochemistry
    Magnetic Resonance Imaging
    Male
    Middle Aged
    Positron-Emission Tomography and Computed Tomography
    Tumor Markers, Biological

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    22681577