Unbound MEDLINE

Urinary sodium to creatinine ratio in healthy infants.

Abstract

Rationale Sodium is essential for adequate growth; the daily requirement in infants is 2 to 3 mmol/kg/d. Objectives The study aimed to establish a reference range for the ratio of urinary sodium (UNa) to creatinine (UCr) in healthy infants in a suburban setting in the United States. Methods UNa and UCr were measured in healthy infants and UNa:UCr was calculated. Daily sodium intake was estimated by parental report. Results Mean estimated sodium intake in the 71 infants was 1.34 mEq/kg/d (95% confidence interval = 1.23-1.44). The mean UNa:UCr was 11.73 (95% confidence interval = 10.24-13.23) and did not differ significantly in age-groups. There was no direct correlation between sodium intake and UNa:UCr in healthy infants. Conclusions The UNa:UCr was 11.73 in this population of healthy infants. This likely reflects the appropriate physiologic response to sodium intake in the study population, which was at the lower end of the usual estimated needs for infants.

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  • Publisher Full Text
  • Authors

    Mann M, Waz W, Poupoulos J, Kadle R, Korn A, Vaughan R, Borowitz D

    Institution

    Baylor College of Medicine, Houston, TX 77030, USA. mcmann@texaschildrenshospital.org

    Source

    Clinical pediatrics 51:9 2012 Sep pg 852-5

    MeSH

    Age Distribution
    Biological Markers
    Creatinine
    Cross-Sectional Studies
    Diet
    Diet Surveys
    Humans
    Infant
    Infant, Newborn
    Linear Models
    New York
    Reference Values
    Sodium
    Sodium, Dietary
    Suburban Health

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    22718704