Abstract

OBJECTIVES
To investigate the risk of hypophosphatemia and hypercalcemia in small for gestational age (SGA) extremely low birth weight infants (ELBWI) receiving parenteral nutrition.
METHODS
A retrospective review of 58 ELBWI was conducted. Serum calcium (Ca) and phosphate (PO4) concentrations on days 1 and 8 after birth were examined for associations with body measurements and nutritional factors in the 1st week of life.
RESULTS
Lower birth weight standard deviation (SD) scores were correlated with hypophosphatemia and hypercalcemia in SGA ELBWI on day 8. Higher parenteral amino acid (AA) administration was correlated with hypophosphatemia on day 8. SGA ELBWI exhibited lower serum PO4 concentrations compared to appropriate for gestational age (AGA) ELBWI on day 8.
CONCLUSIONS
This is the 1st study to report that parenteral nutrition, in the first 7 days after birth for the treatment of SGA ELBWI, was correlated with hypophosphatemia and hypercalcemia. It is important to determine an ideal nutrition protocol for treatment of SGA ELBWI.

Authors

Ichikawa G, Watabe Y, Suzumura H, Sairenchi T, Muto T, Arisaka O

Institution

Department of Pediatrics, Dokkyo Medical University School of Medicine, Mibu, Tochigi, Japan. ichikawa@dokkyomed.ac.jp

Source

Journal of pediatric endocrinology & metabolism : JPEM 25:3-4 2012 pg 317-21

MeSH

Birth Weight
Female
Humans
Hypercalcemia
Hypophosphatemia
Infant, Extremely Low Birth Weight
Infant, Newborn
Infant, Small for Gestational Age
Male
Parenteral Nutrition
Prognosis
Retrospective Studies

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22768663