Abstract

Circadian regulation is essential for optimum plant performance. In addition to loops and cascades of transcription and translation, the plant circadian clock and its associated signal transduction networks incorporate many post-translational mechanisms. Phosphorylation is a common feature of signal transduction and gene regulation. In this opinion article, we illustrate how phosphorylation events are positioned within the entrainment, functioning, and regulation of the circadian timing system. Phosphorylation regulates protein stability, protein-protein interactions and protein-DNA interactions within the core oscillator. We suggest that phosphorylation provides a potential mechanism for the distribution of circadian timing information within the cell and for the integration of circadian timing information with other signaling pathways.

Links

Publisher Full Text

Authors

Kusakina J, Dodd AN

Institution

Department of Biology, University of York, York YO10 5DD, UK.

Source

Trends in plant science 17:10 2012 Oct pg 575-83

MeSH

Arabidopsis
Arabidopsis Proteins
Cell Membrane
Circadian Clocks
Circadian Rhythm
Membrane Transport Proteins
Phosphorylation
Photosynthesis
Protein Interaction Mapping
Protein Processing, Post-Translational
Protein Stability
Signal Transduction
Transcription Factors
Transcription, Genetic

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

22784827