Comparison of 30-day mortality models for profiling hospital performance in acute ischemic stroke with vs without adjustment for stroke severity.
Abstract
CONTEXT
There is increasing interest in reporting risk-standardized outcomes for Medicare beneficiaries hospitalized with acute ischemic
stroke, but whether it is necessary to include adjustment for initial stroke severity has not been well studied.
OBJECTIVE
To evaluate the degree to which hospital outcome ratings and potential eligibility for financial incentives are altered after
including initial stroke severity in a claims-based risk model for hospital 30-day mortality for acute ischemic stroke.
DESIGN, SETTING, AND PATIENTS
Data were analyzed from 782 Get With The Guidelines-Stroke participating hospitals on 127,950 fee-for-service Medicare beneficiaries
with ischemic stroke who had a score documented for the National Institutes of Health Stroke Scale (NIHSS, a 15-item neurological
examination scale with scores from 0 to 42, with higher scores indicating more severe stroke) between April 2003 and December
2009. Performance of claims-based hospital mortality risk models with and without inclusion of NIHSS scores for 30-day mortality
was evaluated and hospital rankings from both models were compared.
MAIN OUTCOMES MEASURES
Model discrimination, hospital 30-day mortality outcome rankings, and value-based purchasing financial incentive categories.
RESULTS
Across the study population, the mean (SD) NIHSS score was 8.23 (8.11) (median, 5; interquartile range, 2-12). There were
18,186 deaths (14.5%) within the first 30 days, including 7430 deaths (5.8%) during the index hospitalization. The hospital
mortality model with NIHSS scores had significantly better discrimination than the model without (C statistic, 0.864; 95%
CI, 0.861-0.867, vs 0.772; 95% CI, 0.769-0.776; P < .001). Among hospitals ranked in the top 20% or bottom 20% of performers
by the claims model without NIHSS scores, 26.3% were ranked differently by the model with NIHSS scores. Of hospitals initially
classified as having "worse than expected" mortality, 57.7% were reclassified to "as expected" by the model with NIHSS scores.
The net reclassification improvement (93.1%; 95% CI, 91.6%-94.6%; P < .001) and integrated discrimination improvement (15.0%;
95% CI, 14.6%-15.3%; P < .001) indexes both demonstrated significant enhancement of model performance after the addition of
NIHSS. Explained variance and model calibration was also improved with the addition of NIHSS scores.
CONCLUSION
Adding stroke severity as measured by the NIHSS to a hospital 30-day risk model based on claims data for Medicare beneficiaries
with acute ischemic stroke was associated with considerably improved model discrimination and change in mortality performance
rankings for a substantial portion of hospitals.
Links
Authors
Fonarow GC, Pan W, Saver JL, Smith EE, Reeves MJ, Broderick JP, Kleindorfer DO, Sacco RL, Olson DM, Hernandez AF, Peterson ED, Schwamm LH
Institution
Division of Cardiology, University of California, Los Angeles, USA. gfonarow@mednet.ucla.edu
Source
JAMA : the journal of the American Medical Association 308:3 2012 Jul 18 pg 257-64MeSH
Acute DiseaseAged
Aged, 80 and over
Brain Ischemia
Female
Forecasting
Hospital Mortality
Hospitals
Humans
Insurance Claim Review
Male
Medicare
Models, Theoretical
Outcome Assessment (Health Care)
Quality Indicators, Health Care
Reimbursement, Incentive
Risk
Severity of Illness Index
Stroke
United States
Pub Type(s)
Comparative StudyJournal Article
Research Support, Non-U.S. Gov't
Language
eng
PubMed ID
22797643
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