Abstract

Benign solitary ulcer of the colon is an uncommon lesion that was originally described by Cruveilhier in 1832. Its aetiology remains unknown, and there are no pathognomonic lesions or symptoms. Diagnosis is made by exclusion; in fact, diseases such as specific infections (cytomegalovirus, campylobacter jejuni, entamoeba histolytica), common clinical conditions (acute appendicitis, diverticulitis, intestinal obstruction, inflammatory bowel disease), pharmacotherapy (non-steroidal anti-inflammatory medications, oral contraceptives, dicumarolic agents) and malignancies should be excluded. We describe the case of a 72-year-old patient admitted for acute bloody diarrhoea, originally misdiagnosed as carcinoma by colonscopy. The histological evaluation demonstrated a benign ulcerative lesion.

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Authors

Ambrosio MR, Ginori A, Mourmouras V, Mastrogiulio MG, Barone A, Rocca BJ

Institution

Department of Human Pathology and Oncology, Anatomic Pathology Section, University of Siena, Italy.

Source

Pathologica 104:1 2012 Feb pg 34-7

MeSH

Aged
Colon
Colonic Diseases
Colonic Neoplasms
Diagnosis, Differential
Diagnostic Errors
Female
Humans
Ulcer

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22799054