Unbound MEDLINE

Radical trachelectomy: a fertility-sparing option for early invasive cervical cancer.

Abstract

For the past 15 years gynecological oncologists have been seeking ways to preserve woman's fertility when treating invasive cervical cancer. For some women with small localized invasive cervical cancers, there is now hope for pregnancy after treatment. Many cases of cervical cancer are diagnosed in young woman who wish to preserve their fertility. As more women are delaying childbearing, fertility preservation has become an important consideration. The standard surgical treatment for stage IA2-IB1 cervical cancer is a radical hysterectomy and bilateral pelvic lymphadenectomy. This surgery includes removal of the uterus and cervix, radical resection of the parametrial tissue and upper vagina, and complete pelvic lymphadenectomy. Obviously, the standard treatment does not allow future childbearing. Radical trachelectomy is a fertility-sparing surgical approach developed in France in 1994 by Dr. Daniel Dargent for the treatment of early invasive cervical cancer. Young women wishing to bear children in the future may be candidates for fertility-preservation options. The radical trachelectomy operation has been described and performed abdominally, assisted vaginally by laparoscopy and robotically. In this review we discuss the selection criteria for radical trachelectomy, the various possible techniques for the operation, the oncological and obstetric outcomes, and common complications.

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  • Publisher Full Text

    • Authors

    Mejia-Gomez J, Feigenber T, Arbel-Alon S, Kogan L, Benshushan A

    Institution

    Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center (Ein Kerem Campus), Jerusalem, Israel.

    Source

    The Israel Medical Association journal : IMAJ 14:5 2012 May pg 324-8

    MeSH

    Adult
    Cerclage, Cervical
    Female
    Humans
    Infertility, Female
    Laparoscopy
    Lymph Node Excision
    Neoplasm Invasiveness
    Neoplasm Recurrence, Local
    Neoplasm Staging
    Postoperative Complications
    Robotics
    Round Ligament
    Surgical Flaps
    Uterine Cervical Neoplasms

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    22799068