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Experimental study of the effects of Dietressa, a new weight-reducing drug.

Abstract

The capacity of a new drug containing ultra-low doses of antibodies to cannabinoid receptor type 1 (Dietressa) to reduce body weight gain in mice on a high-calorie diet was evaluated, possible mechanisms of drug action were analyzed, and its safety (abuse potential in the reaction of self-stimulation) was evaluated. Dietressa was not inferior to sibutramine in reducing body weight gain in mice and exhibited no abuse potential.

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    • Authors

    Kheyfets IA, Bugaeva LI, Vorob'eva TM, Dugina JL, Lebedeva SA, Petrov VI, Sergeeva SA, Epstein OI

    Institution

    Materia Medica Holding, Moscow, Russia. nauka@materiamedica.ru

    Source

    Bulletin of experimental biology and medicine 152:3 2012 Jan pg 321-4

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    22803076