Abstract

Myxoinflammatory fibroblastic sarcoma (MIFS) is a rare low-grade tumor of modified fibroblasts, with tendency to local recurrence. This unusual entity typically presents as a slow-growing painless mass in the distal extremities of middle-aged subjects. A 48-year-old woman presented to our clinic with a painless subcutaneous mass in the right temporal region. Excisional biopsy made the rare diagnosis of MIFS. Histologic examination showed the unique features that characterize this lesion: a myxoid component with a superimposed inflammatory infiltrate and the presence of distinctive, large, and bizarre Reed-Stemberg-like cells. A second wide tumor bed resection was performed, achieving clear margins. No adjuvant therapy was administered, and the patient is free of disease at 18 months postoperatively. To the best of our knowledge, this is the first reported case of MIFS presenting in the face. This adds another possibility for differential diagnoses of soft tissue tumors of the face.

Links

Publisher Full Text

Authors

Gómez Martín C, Ortega MI, Aramburu JA, Fernández-Cañamaque JL

Institution

Department of Plastic and Reconstructive Surgery, Hospital Universitario de Getafe, Madrid, Spain. cristinnagm@hotmail.com

Source

The American Journal of dermatopathology 34:6 2012 Aug pg 663-5

MeSH

Dermatologic Surgical Procedures
Face
Female
Fibroblasts
Humans
Middle Aged
Sarcoma
Skin Neoplasms
Treatment Outcome

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22814322