Abstract
BACKGROUND/AIMS
Platelet count-to-spleen diameter ratio is reported to be the best non-invasive predictor of esophageal varices in cirrhotic
patients. However, spleen enlargement is frequently detected during follow-up of patients after gastrectomy. Thus, we studied
the relationship of the platelet count-to-spleen diameter ratio with the development of esophageal varices after distal gastrectomy
in patients without liver cirrhosis or hepatitis.
METHODOLOGY
We retrospectively studied 64 patients who underwent distal gastrectomy. Their platelet counts, spleen diameters and platelet
count-to-spleen diameter ratios were correlated with the occurrence rate of esophageal varices after the surgery.
RESULTS
Esophageal varices were not detected during the first 6 months after surgery; however, esophageal varices were detected in
2 patients (3%) at 12 months after surgery and their mean platelet count-to-spleen diameter ratio was 2,628 ± 409.
CONCLUSIONS
The platelet count-to-spleen diameter ratio is a useful parameter for non-invasive prediction of esophageal varices after
distal gastrectomy. In addition, we suggest that the occurrence rate of esophageal varices increases beyond 6 months after
distal gastrectomy and when the platelet count-to-spleen diameter ratio is less than approximately 2600 and thus, endoscopy
should be performed to determine the presence of esophageal varices.
Authors
Oida T, Mimatsu K, Kano H, Kawasaki A, Kuboi Y, Fukino N, Kida K, Amano S
Institution
Department of Surgery, Social Insurance Yokohama Central Hospital, Yokohama, Japan. ooida.takatsugu@yokochu.jp
Source
Hepato-gastroenterology 59:118 2012 Sep pg 2008-11MeSH
AgedChi-Square Distribution
Endoscopy, Gastrointestinal
Esophageal and Gastric Varices
Female
Gastrectomy
Humans
Male
Middle Aged
Platelet Count
Predictive Value of Tests
Retrospective Studies
Splenomegaly
Time Factors
Treatment Outcome
Pub Type(s)
Journal ArticleLanguage
eng
PubMed ID
22819919
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