Abstract

We present our surveillance results on imported dengue cases in Taiwan during 2008-2010. A total of 734 imported dengue patients were identified. The travelers were arriving from 18 countries, including Southeast Asia, the Indian subcontinent, South Pacific islands, and Latin America. Gene sequences from 358 dengue virus (DENV) isolates were used to perform phylogenetic analyses, thus, providing an updated view of the geographic distribution and dynamic transmission of DENV strains circulating in these countries. Our results suggest that the DENV-1 genotype I and DENV-2 Cosmopolitan genotype comprise the predominant DENV strains circulating in Southeast Asian countries. The DENV-3 Genotype III strain was found to be newly emerging in several Southeast Asian countries, however, the Asian genotype 2 and the Asian/American genotype of DENV-2 strains appeared to be less prevalent in Southeast Asia. Furthermore, imported dengue viruses are representative of the overall patterns of serotype/genotype frequencies of dengue outbreaks that occurred in Taiwan.

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Publisher Full Text

Authors

Huang JH, Su CL, Yang CF, Liao TL, Hsu TC, Chang SF, Lin CC, Shu PY

Institution

Research and Diagnostic Center, Centers for Disease Control, Department of Health, Taipei, Taiwan, Republic of China.

Source

The American journal of tropical medicine and hygiene 87:2 2012 Aug pg 349-58

MeSH

Antibodies, Viral
Base Sequence
Dengue
Dengue Virus
Genotype
Humans
Molecular Sequence Data
Phylogeny
RNA, Viral
Real-Time Polymerase Chain Reaction
Sequence Analysis, DNA
Taiwan

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22855770