Abstract

Amyloidosis is an uncommon syndrome consisting of a number of disorders having in common an extracellular deposit of fibrillary proteins. This results in functional and structural changes in the affected organs, depending on deposit location and severity. Amyloid infiltration of the thyroid gland may occur in 50% and up to 80% of patients with primary and secondary amyloidosis respectively. Amyloid goiter (AG) is a true rarity, usually found associated to secondary amyloidosis. AG may require surgical excision, usually because of compressive symptoms. We report the case of a patient with a big AG occurring in the course of a secondary amyloidosis associated to polyarticular onset juvenile idiopathic arthritis who underwent total thyroidectomy. Current literature is reviewed, an attempt is made to provide action guidelines, and some surgical considerations on this rare condition are given.

Links

Publisher Full Text

Authors

García Villanueva A, García Villanueva MJ, García Villanueva M, Rojo Blanco R, Collado Guirao MV, Cabañas Montero J, Beni Pérez R, Moreno Montes I

Institution

Unidad de Cirugía General y Digestiva, Hospital Universitario Ramón y Cajal, Madrid, España. Electronic address: garciavillanueva@gmail.com.

Source

Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 60:5 2013 May pg 254-259

Pub Type(s)

JOURNAL ARTICLE

Language

ENG SPA

PubMed ID

22867857