High-performance liquid chromatographic determination of alpha-tocopherol in inclusion complexes with cyclodextrins.
A new high performance liquid chromatography (HPLC)-based method is proposed for the determination of vitamin E, free and in inclusion complexes with natural beta-cyclodextrin and its 2-hydroxy derivative. The method has been validated on the basis of the following parameters: specificity, selectivity, linearity, precision, range and recovery.
Department of Inorganic and Analytical Chemistry, Karol Marcinkowski University of Medical Sciences, Grunwaldzka 6, 60-780 Poznań, Poland.
SourceActa poloniae pharmaceutica 69:4 pg 591-5
Chromatography, High Pressure Liquid
Hydrophobic and Hydrophilic Interactions
Reproducibility of Results
Sensitivity and Specificity
Pub Type(s)Journal Article