Unbound MEDLINE

Sedentary behavior, physical activity, and markers of health in older adults.

Abstract

INTRODUCTION
The purpose of this study was to examine the association between sedentary behavior (SB), cardiometabolic risk factors, and self-reported physical function by level of moderate-vigorous physical activity (MVPA).
METHODS
Cross-sectional analysis was completed on 1914 older adults age ≥ 65 yr from the 2003-2006 U.S. National Health and Nutrition Examination Survey. MVPA and SB were derived from ActiGraph accelerometers worn for 1 wk. MVPA was categorized as sufficient to meet the current U.S. guidelines (≥ 150 min · wk(-1)) or not; SB was split into quartiles. Various biomarkers were examined in laboratory analyses and physical exams, and the number of functional limitations was self-reported. Statistical interaction between SB and MVPA on the biomarker associations was the primary analysis, followed by an examination of their independent associations with relevant covariate adjustment.
RESULTS
Average SB was 9.4 ± 2.3 h · d(-1) (mean ± SD), and approximately 35% were classified as sufficiently active. Overall, no significant meaningful statistical interactions were found between SB and MVPA for any of the outcomes; however, strong independent positive associations were found between SB and weight (P < 0.01), body mass index (P < 0.01), waist circumference (P < 0.01), C-reactive protein (P < 0.01), plasma glucose (P = 0.04), and number of functional limitations (P < 0.01) after adjustment for MVPA. Similarly, MVPA was negatively associated with weight (P = 0.01), body mass index (P < 0.01), waist circumference (P < 0.01), diastolic blood pressure (P = 0.04), C-reactive protein (P < 0.01), and number of functional limitations (P < 0.01) after adjustment for SB.
CONCLUSIONS
The results suggest that sufficient MVPA did not ameliorate the negative associations between SB and cardiometabolic risk factors or functional limitations in the current sample and that there was independence on a multiplicative scale in their associations with the outcomes examined. Thus, older adults may benefit from the joint prescription to accumulate adequate MVPA and avoid prolonged sitting.

Links

  • Publisher Full Text
  • Authors

    Gennuso KP, Gangnon RE, Matthews CE, Thraen-Borowski KM, Colbert LH

    Source

    Medicine and science in sports and exercise 45:8 2013 Aug pg 1493-500

    MeSH

    Adult
    Aged
    Biological Markers
    Cardiovascular System
    Cross-Sectional Studies
    Exercise
    Female
    Health Status Indicators
    Health Surveys
    Humans
    Male
    Middle Aged
    Risk Assessment
    Risk Factors
    Sedentary Lifestyle
    United States

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    23475142