Abstract

A half-sided, single-blind, comparative study of a new modified formulation of 1% hydrocortisone/10% urea and 0.1% betamethasone valerate cream in the treatment of dry eczema showed that the two products were equally effective at the end of 1, 2 and 3 weeks of treatment in terms of efficacy and speed of action. No statistically significant differences could be detected between either preparation in any of the trial's measures (i.e. overall severity score, dryness/scaling, erythema, papules, itching, excoriation or lichenification) at any of the weekly assessments. The incidence of side-effects was the same with both treatments and patients' preference was equally divided between the two creams.

Authors

Williamson DM

Source

The Journal of international medical research 15:2 pg 99-105

MeSH

Administration, Topical
Adult
Anti-Inflammatory Agents
Betamethasone
Betamethasone 17-Valerate
Drug Combinations
Eczema
Female
Humans
Hydrocortisone
Male
Middle Aged
Ointments
Random Allocation
Urea

Pub Type(s)

Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

3582724