Abstract

A severe exudative-crustous and proliferous dermatitis in a 2 year old sheep caused by Dermatophilus congolensis (observed for the first time in Italy), is reported. The disease was reproduced experimentally in sheep, goats, rabbits and guinea pigs, whose skin was treated in different ways before infection. E.L.I.S.A. and Immunoblotting tests carried out in experimentally infected sheep, showed the antigenic complexity of the pathogen and the existence of cross-immunity to the protein components. Intradermoreaction tests were carried out in all animals. The development of a positive reaction only in rabbits and guinea pigs, confirmed that these animals have a cellular immunity against Dermatophilus congolensis.

Authors

Leoni A, Fadda M, Nieddu AM, Pittau M, Sanna E, Pirino S, Contini A

Institution

Istituto di Patologia Generale e Anatomia Patologica Veterinaria, Università degli Studi di Sassari.

Source

Bollettino della Società italiana di biologia sperimentale 69:12 1993 Dec pg 775-82

MeSH

Actinomycetales
Actinomycetales Infections
Animals
Antibodies, Fungal
Dermatitis
Goats
Guinea Pigs
Mice
Rabbits
Sheep
Sheep Diseases

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8003293