- A case of myxoid chondrosarcoma arising from caput costae. [Case Reports]Ai Zheng. 2009 Aug; 28(8):894-6.AZ
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- [Vascular endothelial growth factor (VEGF)-D in association with VEGF receptor-3 in lymphatic metastasis of breast cancer]. [Review]
- Breast carcinoma is the most common malignant tumor in women. For these patients, lymph node metastasis is one of the most important prognostic factors. Recent studies suggest that lymphangiogenesis can contribute to the lymphatic metastasis in tumors. Several members of vascular endothelial growth factor (VEGF) family, such as VEGF-C, VEGF-D, and VEGF receptor-3 (VEGFR-3), have been found to pro…
- [Progress on the subcellular localization of Daxx]. [Review]
- As a highly conserved nuclear protein, death domain-associated protein(Daxx) plays an important role in transcriptional control, carcinogenesis, resistance to virus infection, and so on. Daxx can be localized in promyleocytic leukaemia protein oncogenic domains, nucleoplasm, nucleolus, cytoplasm, and heterochromatin. The subcellular localization of Daxx can be changed by modification or interacti…
- [Expression of B7-H1 protein in human pancreatic carcinoma tissues and its clinical significance]. [Journal Article]
- CONCLUSIONS: B7-H1 protein was expressed in human pancreatic carcinoma tissues, and was associated with the prognosis.
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- [Clinical research on recombinant human Ad-p53 injection combined with cisplatin in treatment of malignant pleural effusion induced by lung cancer]. [Randomized Controlled Trial]
- CONCLUSIONS: rAd-p53 and cisplatin is safe and effective for malignant pleural effusion induced by lung cancer. It is worthy of application in clinical treatment.
- [Efficacy of cetuximab combined with chemotherapy on advanced colorectal cancer: a report of 53 cases]. [Journal Article]
- CONCLUSIONS: Cetuximab combined with chemotherapy can achieve relatively high disease control rate for ACRC patients, with less adverse events. Whether cetuximab has better effect in first-line treatment than in non-first-line treatment needs further study.
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- [Clinical characteristics and prognosis of very young patients with breast cancer in the southern of China]. [Journal Article]
- CONCLUSIONS: Compared with non-young premenopausal patients, very young breast patients with HR-positive cancer have a worse outcome.
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- [Efficacy and survival of 92 cases of Ewing's sarcoma family of tumor initially treated with multidisciplinary therapy]. [Journal Article]
- CONCLUSIONS: Our studying showed multidisciplinary therapy could significantly improve non-metastatic ESFT patients' survival. Chemotherapy plus surgery and plus radiation or not were superior to chemotherapy plus radiation in local control for the non-metastatic ESFT. Therapy model and response were independent prognostic factors.
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- [Correlation of hypermethylation of TSP1 gene with TGF-beta1 level and T cell immunity in gastric cardia adenocarcinoma]. [Journal Article]
- CONCLUSIONS: Promoter hypermethylation of TSP1 may play an important role in the development of GCA and reflect the biological behaviours of GCA.
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- [Correlation of the sensitivity of NP chemotherapy in non-small lung cancer with DNA repair gene XRCC1 polymorphism]. [Journal Article]
- CONCLUSIONS: The sensitivity to NP chemotherapy significantly increased in the NSCLC patients with XRCC1 194 CT and TT genotypes compared with those with CC genotype. XRCC1 codon 194 and codon 399 polymorphisms may be used to predict the sensitivity of NSCLC to NP chemotherapy.
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- [LRP16 gene function based on bioinformatic analysis]. [Journal Article]Ai Zheng. 2009 Dec; 28(12):1283-90.AZ
- CONCLUSIONS: Promoter regulation prediction and protein domain analysis based on bioinformatics contribute to the study of gene function. LRP16 may play an important role in leukemia progression by promoting cell proliferation, regulating cell cycle, and antagonizing radiation-induced DNA damage.
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- [Expression of TEIF protein in colorectal tumors and its correlation with centrosome abnormality]. [Journal Article]
- CONCLUSIONS: TEIF protein and centrosome amplification is commonly found in colorectal tumors. The expression level of TEIF is related to tumor histological grade and malignant degree. TEIF protein expression and centrosome amplification showed a high degree of positive correlation.
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- [Synergistic cytotoxicity effect of histone deacetylase inhibitor combined with paclitaxel on lung cancer cell lines and its mechanism]. [Journal Article]
- CONCLUSIONS: TSA combined with paclitaxel has a synergistic cytotoxicity effect on lung cancer cell lines H322 and H1299 when the cells were treated with TSA followed by paclitaxel. The mechanism may be that TSA down-regulates the survivin high-expression induced by paclitaxel, and blocks pERK protein expression.
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- [Feasibility and short-term efficacy of simplified intensity-modulated radiotherapy and concurrent chemotherapy for neck and upper thoracic esophageal carcinoma]. [Journal Article]
- CONCLUSIONS: sIMRT can generate desirable dose distribution for neck and upper thoracic esophageal carcinoma, which is similar to sophisticated IMRT but obviously better than 3D-CRT. The short-term efficacy of sIMRT is satisfactory and its acute toxicities are tolerable.
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- [Efficacy of surgical resection of left and right transthoracic approaches for middle thoracic esophageal squamous cell carcinoma]. [Journal Article]
- CONCLUSIONS: Although left transthoracic resection reduced the incidence of postoperative complications, esophagectomy of right transthoracic approach was more effective in survival improvement.