(Allergy[TA])
16,243 results
  • MUC16 Defines a Fibrotic Endotype With Corticosteroid Insensitivity in Nasal Polyps. [Journal Article]
    Allergy. 2026 Oct 16. [Online ahead of print]Montero P, Roger I, … Milara JA
  • CONCLUSIONS: In human polyp tissue, MUC16 is associated with a fibrotic, corticosteroid-insensitive CRSwNP phenotype, whereas its causal link with impaired glucocorticoid signaling is supported by in vitro loss-of-function experiments. MUC16 may represent a candidate biomarker and potential therapeutic target in refractory CRSwNP, although prospective validation as an endotype-defining biomarker is still required.