- Treating co-occurring alcohol use disorder and major depressive disorder: A systematic review of combination and multimodal pharmacotherapy. [Review]Am J Addict. 2026 Oct 04. [Online ahead of print]AJ
- CONCLUSIONS: Converging dopaminergic, serotonergic, glutamatergic, opioidergic, and neuroimmune mechanisms support combined pharmacotherapy, but the evidence base remains thin, underpowered, and unreplicated. Available evidence and current integrated-care approaches favor concurrent rather than sequential treatment of AUD and MDD, although the evidence supporting specific pharmacological combinations remains limited.
- Publisher Full Text (DOI)
- Gambling behaviors associated with problem gambling among patients in treatment for substance use disorder. [Journal Article]Am J Addict. 2026 Sep 27. [Online ahead of print]AJ
- CONCLUSIONS: Specific gambling behaviors increase risk of problem gambling for SUD patients. SUD treatment programs should screen for and address problem gambling.
- Publisher Full Text (DOI)
- Evidence-based harm reduction training via ECHO: A mentor facilitated educational training for behavioral health providers. [Journal Article]Am J Addict. 2026 Sep 22. [Online ahead of print]AJ
- CONCLUSIONS: ECHO-based harm reduction training was feasible and associated with meaningful improvements in provider knowledge, relevance, and intention to implement harm reduction strategies.
- Publisher Full Text (DOI)
- Opioid withdrawal syndrome-associated cognitive impairment: A narrative review. [Review]Am J Addict. 2026 Sep 17. [Online ahead of print]AJ
- CONCLUSIONS: Future studies on OWSCI entailing more rigorous experimental controls and standardizations, while accounting for diverse comorbidities and OWS treatments, are needed to more fully characterize OWSCI.
- Publisher Full Text (DOI)
- How common is alcohol use disorder in posttraumatic stress disorder? A systematic review, meta-analysis, and moderator analysis. [Review]Am J Addict. 2026 Sep 16. [Online ahead of print]AJ
- CONCLUSIONS: This review identifies sample characteristics that moderate AUD burden within PTSD populations: clinical settings, inpatient care, and veteran status predict higher prevalence, whereas greater female representation predicts lower rates. These findings support population-specific screening and integrated, trauma-informed care.
- Publisher Full Text (DOI)
- Clinical applications of wearable devices for individuals with at-risk substance use and substance use disorders: A systematic review. [Review]Am J Addict. 2026 Sep 09. [Online ahead of print]AJ
- CONCLUSIONS: Wearable devices show promise as adjunct tools for monitoring clinically relevant indicators in SUDs, but evidence remains limited. Future research should prioritize longitudinal outcomes, validate clinically meaningful thresholds, and support equitable, patient-centered implementation.
- Publisher Full Text (DOI)
- Proof-of-concept trial of PP-01 for mitigating cannabis withdrawal syndrome in participants with cannabis use disorder. [Journal Article]Am J Addict. 2026 Sep 09. [Online ahead of print]AJ
- CONCLUSIONS: Investigational PP-01 mitigated cannabis withdrawal symptoms in participants with moderate to severe CUD, was safe and well-tolerated in this proof-of-concept study.
- Publisher Full Text (DOI)
- Gambling disorder in late life: A systematic review of behavioral patterns, clinical correlates, and psychotherapeutic interventions. [Review]Am J Addict. 2026 Jul 18. [Online ahead of print]AJ
- CONCLUSIONS: Current evidence highlights substantial gaps in age-specific assessment and targeted interventions. Future studies should prioritize tailored psychological interventions addressing loneliness, emotional regulation, cognitive distortions, and life transitions in later adulthood.
- Publisher Full Text (DOI)
- Extended-release buprenorphine in adults with opioid use disorder involving poppy seed tea: An 18-month retrospective case series. [Case Reports]
- CONCLUSIONS: BUP-XR assisted stability within multidisciplinary care.
- PMC Free PDF
- Alcohol exclusion provisions and alcohol-related insurance claim denials in the United States: A narrative review. [Review]Am J Addict. 2026 Jul 14. [Online ahead of print]AJ
- CONCLUSIONS: Legal heterogeneity remains substantial and may contribute to policy misclassification and biased estimates in empirical evaluations of AEPs.
- Publisher Full Text (DOI)
- Rural-urban residence in relation to cannabis use influences and behaviors among a sample of US young adults reporting past-month cannabis use. [Journal Article]
- CONCLUSIONS: Rural (vs. urban) young adults reported more frequent cannabis use and DUIC, which may be associated with low cannabis-related harm perceptions and using cannabis to cope with stress/mental health symptoms.
- PMC Free PDF
- Do motives for and contexts of cannabis use interact to predict heavy cannabis use at the event-level? [Journal Article]
- CONCLUSIONS: Findings indicated that coping motives were only associated with CU when combined with solitary use. Social and enhancement motives and social contexts produced additive effects.
- PMC Free PDF
- Risks of alcohol-energy drink co-consumption: Patterns, correlates and psychological outcomes in youth. [Journal Article]
- CONCLUSIONS: AmED consumption is common among Spanish youth and is more strongly linked to polysubstance use and poor mental health than alcohol use alone.
- PMC Free PDF
- Brief report: A cross-sectional survey of provider engagement with family members following patient drug overdose death. [Journal Article]
- CONCLUSIONS: Providers inconsistently contacted families despite believing these interactions are opportunities to improve family and provider coping.
- PMC Free PDF