Influenza vaccination among healthcare personnel has declined nationwide since the COVID-19 pandemic began in 2020. We surveyed acute care hospitals within Los Angeles County to examine worker attitudes regarding influenza vaccination and the impact of COVID-19. Comparing before and during the pandemic, we found increased safety and efficacy concerns, and decreased perception of disease severity and risk of influenza, suggesting that redundancy of established COVID-19 measures and pandemic fatigue may have contributed to vaccine refusal.

This matched case-control study evaluated 318 hospitalized patients with central venous catheters between 2018 and 2022 to identify risk factors for central line-associated bloodstream infection. Independent risk factors included immunosuppression, longer catheter dwell time, and prolonged hospitalization. Klebsiella pneumoniae predominated among isolates, and the pandemic period was associated with increased carbapenem and quinolone resistance, highlighting the need for sustained infection prevention and antimicrobial stewardship strategies.