- Classification of difficult direct laryngoscopy using the VIDIAC score: a prospective external validation study. [Journal Article]Anaesthesia. 2026 Oct 14. [Online ahead of print]A
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- Impact of clinical frailty on mortality after elective surgery in patients aged ≥ 90 years admitted to critical care: a binational intensive care registry analysis. [Journal Article]Anaesthesia. 2026 Oct 13. [Online ahead of print]A
- CONCLUSIONS: Among patients aged ≥ 90 years undergoing elective surgery with postoperative intensive care admission, frailty is strongly associated with prolonged recovery and worse short and long-term outcomes. Incorporation of frailty assessment into peri-operative pathways may improve risk stratification, shared decision-making and personalised care for patients aged ≥ 90 years.
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- Incidence and reasons for cancellation on the day of elective surgery: a systematic review and meta-analysis. [Review]Anaesthesia. 2026 Oct 12. [Online ahead of print]A
- CONCLUSIONS: Cancellation on the day of surgery remains a substantial and globally relevant peri-operative problem. Its burden and drivers are highly context-dependent and often reflect weaknesses in pre-operative preparation, organisational co-ordination and system capacity. Reducing avoidable cancellations may therefore require context-specific strategies targeting pathway reliability, timely pre-anaesthetic assessment and peri-operative resource alignment.
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- Association of pre-operative opioid use disorder and postoperative outcomes: a systematic review and meta-analysis. [Review]Anaesthesia. 2026 Oct 12. [Online ahead of print]A
- CONCLUSIONS: Our results suggest that opioid use disorder is associated with higher incidence of postoperative pain, increased postoperative complications and greater total healthcare costs, which supports the need for routine pre-operative screening for opioid use disorder and the application of patient-centred, multidisciplinary peri-operative care and pain management.
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- PUMA tracheal extubation guidelines: towards clarity or complexity? [Editorial]Anaesthesia. 2026 Oct 07. [Online ahead of print]A
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- Infiltration between the popliteal artery and the capsule of the knee (IPACK) vs. selective tibial nerve block for analgesia after anterior cruciate ligament reconstruction: a randomised controlled trial. [Journal Article]Anaesthesia. 2026 Oct 06. [Online ahead of print]A
- CONCLUSIONS: The IPACK and selective tibial nerve block provide comparable postoperative analgesia after anterior cruciate ligament reconstruction under general anaesthesia with a femoral triangle block, with similar impact on functional outcomes.
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- Effect of intensive care unit sedation strategy on patient-reported experience: secondary mediation analysis of the A2B randomised controlled trial. [Journal Article]Anaesthesia. 2026 Oct 06. [Online ahead of print]A
- CONCLUSIONS: Dexmedetomidine compared with propofol sedation strategy may be associated with increased recalled awareness of surroundings, which is considered a favourable indicator of ICU experience. Together with the primary A2B trial results, which showed no effect on ventilation duration, these hypothesis-generating findings in a subgroup of the A2B cohort do not support the use of dexmedetomidine over propofol based on patient-reported experience. Based on our findings, we advocate that a personalised approach to sedation strategies should continue to be used.
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- Intra-operative hypotension threshold models and subdistribution hazard of postoperative pneumonia in patients having non-cardiac surgery. [Journal Article]Anaesthesia. 2026 Oct 02. [Online ahead of print]A
- CONCLUSIONS: Intra-operative hypotension was associated with postoperative pneumonia when defined as a relative reduction from baseline mean arterial pressure, whereas conventional absolute thresholds were less informative. These findings suggest that maintaining intra-operative blood pressure close to baseline may be more relevant to pulmonary risk than relying on fixed absolute thresholds alone.
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- Association between glottic view and tracheal intubation during videolaryngoscopy: a prospective observational study. [Journal Article]Anaesthesia. 2026 Oct 02. [Online ahead of print]A
- CONCLUSIONS: The ease of tracheal intubation with videolaryngoscopy cannot be inferred from glottic view alone. A structured approach that incorporates what was used, what was seen and what was done may improve communication in clinical practice.
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- Renal oxygenation, function and histopathology in an ovine model of heart failure undergoing cardiopulmonary bypass with 48 hours of recovery: a prospective, observational study. [Journal Article]Anaesthesia. 2026 Sep 29. [Online ahead of print]A
- CONCLUSIONS: In this ovine model of heart failure, cardiopulmonary bypass led to persistent renal medullary hypoxia, oliguria and increased renal inflammation. These findings suggest that impaired renal medullary oxygenation and inflammation may drive cardiac surgery-associated acute kidney injury and represent a key target for renoprotective strategies.
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- Effects of ultrasound-guided ipsilateral internal jugular vein compression on catheter malposition during ultrasound-guided right infraclavicular subclavian venous catheterisation: a randomised controlled trial. [Journal Article]Anaesthesia. 2026 Sep 24. [Online ahead of print]A
- CONCLUSIONS: Ultrasound-guided ipsilateral IJV compression during guidewire advancement can be an effective intervention to prevent catheter malposition during ultrasound-guided right infraclavicular subclavian venous catheterisation.
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- Pain management after caesarean delivery: beyond analgesia towards holistic maternal recovery. [Editorial]Anaesthesia. 2026 Sep 24. [Online ahead of print]A
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- Burden of chronic postsurgical pain after caesarean delivery on maternal quality of life: a systematic review. [Review]Anaesthesia. 2026 Sep 24. [Online ahead of print]A
- CONCLUSIONS: Chronic postsurgical pain after caesarean delivery is associated with clinically important impairment across multiple domains of quality of life. Early postpartum disruption appears more strongly characterised by functional limitation, whereas affective and psychosocial interference may become relatively more prominent over time. These findings support a multidimensional understanding of persistent pain and recovery after caesarean delivery, and underscore the limitations of assessing pain intensity alone as an outcome in perioperative research.
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- Time to ask a different question: setting new goals for oncoanaesthesia. [Editorial]Anaesthesia. 2026 Sep 24. [Online ahead of print]A
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- Minimal clinically important difference and psychometric properties of the Obstetric Quality of Recovery-10 measure: a systematic review and network meta-analysis. [Review]
- CONCLUSIONS: We recommend using a minimal clinically important difference of 7-10 points for ObsQoR-10, with 7 points as the lower-bound estimate. This can be used to help interpret ObsQoR-10 scores in clinical settings and to power future studies using ObsQoR-10 as a primary outcome measure.
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