- Reconnecting the disconnected forebrain: multimodal resting-state bold dynamics underlying zolpidem-induced arousal in incomplete Locked-in syndrome. [Journal Article]Brain Inj. 2026 Oct 06; :1-11. [Online ahead of print]BI
- CONCLUSIONS: Paradoxical awakening in incomplete LIS is underpinned by structural preservation of the supratentorial mantle. Beyond classical mesocircuit release, zolpidem engages brainstem gating structures, restoring modular segregation, infraslow frequency tuning, and cognitive-motor coupling.
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- Timing matters in acute on-pitch concussion assessment. [Journal Article]Brain Inj. 2026 Oct 01; :1-2. [Online ahead of print]BI
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- Frequency and diagnostic yield of CRPS-I in TBI: a 12-year retrospective cohort study at a Level I trauma center. [Journal Article]Brain Inj. 2026 Oct 01; :1-6. [Online ahead of print]BI
- CONCLUSIONS: The 0.42% frequency underestimates true CRPS-I prevalence due to selective testing. However, a 19.5% diagnostic yield reveals significant under-recognition in cognitively impaired patients when relying on symptom-based criteria. Edema and motor limitation may serve as practical triggers for adjunctive TPBS evaluation in non-communicative survivors.
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- Comparison of recommendations for initial adult traumatic brain injury management across clinical practice guidelines and consensus statements: a scoping review. [Review]Brain Inj. 2026 Oct 01; :1-12. [Online ahead of print]BI
- CONCLUSIONS: Although the fundamental principles of care were largely consistent, important differences remain in their operational implementation. Greater harmonization of clinical definitions and management pathways may facilitate more consistent application of evidence-based recommendations across healthcare settings.
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- Feasibility and preliminary validation of the LIBRA model among those with mild TBI. [Journal Article]Brain Inj. 2026 Sep 29; :1-10. [Online ahead of print]BI
- CONCLUSIONS: Differences in LIBRA scores and other drivers of risk (non-LIBRA) across two mTBI cohorts (acute, historical) support the feasibility of implementation among those with a history of mTBI.
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- Health anxiety following subarachnoid hemorrhage: preliminary insights from a neuropsychology care pathway. [Journal Article]Brain Inj. 2026 Sep 29; :1-9. [Online ahead of print]BI
- CONCLUSIONS: Around one in four individuals reported elevated health anxiety, with 10% meeting the threshold for clinically significant symptoms. The strongest association was with psychological distress, suggesting health anxiety may represent a target for intervention. Further prospective studies are needed to replicate findings and better understand the role of health anxiety in this population.
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- Prognostic role of hemoglobin-to-RDW ratio for clinical outcomes in traumatic brain injury patients admitted to the intensive care unit: a retrospective analysis. [Journal Article]Brain Inj. 2026 Sep 22; :1-7. [Online ahead of print]BI
- CONCLUSIONS: A higher HRR was independently associated with a lower likelihood of prolonged hospital stay among patients with TBI admitted to the ICU. However, HRR was not significantly associated with in-hospital mortality after adjustment.
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- Psychiatric comorbidities in people with and without post-traumatic epilepsy: a systematic review and meta-analysis. [Journal Article]Brain Inj. 2026 Sep 21; :1-7. [Online ahead of print]BI
- CONCLUSIONS: Previous evidence is sparse. We observed no significant difference in depression incidence in PTE vs. TBI-no-epilepsy. Future research should explore psychiatric comorbidities in PTE vs. TBI-no-epilepsy, epilepsy-only, and healthy controls.
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- Caspase-3 dependent, induction of barrier dysfunction and hyperpermeability in blood-brain barrier endothelial cells. [Journal Article]Brain Inj. 2026 Sep 18; :1-9. [Online ahead of print]BI
- Blood-brain barrier (BBB) dysfunction and associated microvascular hyperpermeability lead to brain edema and elevation of intracranial pressure in traumatic and ischemic brain injuries. Pro-inflammatory cytokines, interleukin (IL-1β) and tumor necrosis factor (TNF-α), are up-regulated in such conditions and serve as endogenous activators of caspase-3 and apoptosis. The objective of this study was…
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- What happens when an athlete suffers a concussion outside of sport? An in-depth analysis of non-sport-related concussion in adolescent athletes. [Journal Article]Brain Inj. 2026 Sep; 40(12):1107-1114.BI
- CONCLUSIONS: Non-SRCs show heterogeneous recovery patterns. Findings support applying graduated RTP frameworks to non-SRC management.
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- Developmental eye movement test performance and oculomotor dysfunction in adults with chronic mild traumatic brain injury. [Journal Article]Brain Inj. 2026 Sep 08; :1-8. [Online ahead of print]BI
- CONCLUSIONS: Longer DEM completion times, but not the DEM Ratio, were associated with clinically diagnosed oculomotor dysfunction in adults with chronic mTBI. Total DEM time demonstrated moderate screening performance and may help identify individuals who warrant a comprehensive evaluation.
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- Sex differences in concussion incidence before and during the COVID-19 pandemic: a population-based study (2017-2022). [Journal Article]Brain Inj. 2026 Sep 07; :1-9. [Online ahead of print]BI
- CONCLUSIONS: The pandemic significantly altered healthcare-recorded concussion patterns, likely reflecting both reduced exposure to injury risk and pandemic-related changes in healthcare-seeking and case capture. Our findings underscore the need to incorporate sex as a key variable in future concussion research and prevention strategies.
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- Examining longitudinal changes in alexithymia and depressive symptoms following acquired brain injury. [Journal Article]Brain Inj. 2026 Sep 03; :1-10. [Online ahead of print]BI
- CONCLUSIONS: These findings suggest that alexithymia is relatively stable in the first two years following ABI and commonly co-occurs with depressive symptoms early after injury. However, there is no clear longitudinal direction association. Early assessment of emotional processing and mood may help identify individuals at risk for ongoing psychological difficulties.
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- Association of transcranial Doppler and carotid ultrasound parameters with swallowing outcomes after endovascular thrombectomy for anterior circulation stroke. [Journal Article]Brain Inj. 2026 Sep 02; :1-9. [Online ahead of print]BI
- CONCLUSIONS: Ultrasound-derived hemodynamic parameters were associated with swallowing outcomes after EVT, but the incremental prognostic value of BA PI beyond clinical factors was limited and requires prospective validation.
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- Prospective validation of a non-invasive bedside protocol for tracheostomy decannulation in acquired brain injury with otolaryngologic concordance. [Journal Article]Brain Inj. 2026 Sep; 40(12):1115-1124.BI
- CONCLUSIONS: The bedside protocol may serve as a screening tool to support decannulation assessment and guide the need for confirmatory endoscopic evaluation. Larger multicentre studies are warranted.
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