- PlGF in pulmonary hypertension: addressing the angiogenesis paradox via immune remodeling. [Journal Article]Cardiovasc Res. 2026 Oct 03. [Online ahead of print]CR
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- A shift in the platelet lipidome correlates with platelet differentiation into distinct subfractions in patients with pulmonary embolism. [Journal Article]Cardiovasc Res. 2026 Oct 01. [Online ahead of print]CR
- CONCLUSIONS: Specific stimuli can activate distinct metabolic programmes, leading to remodelling of the platelet lipidome that may influence the differentiation of platelets into separate phenotypic subpopulations in PE.
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- Comorbidity-specific molecular programmes of early diastolic dysfunction identify glucocorticoid receptor activation as a causal driver in obesity. [Journal Article]Cardiovasc Res. 2026 Sep 30. [Online ahead of print]CR
- CONCLUSIONS: Early diastolic dysfunction arises through comorbidity-specific molecular programmes. OB-induced GR activation emerges as a causal and actionable driver of diastolic dysfunction. These findings provide mechanistic insight into comorbidity-specific pathways in HFpEF and support the development of stratified therapeutic approaches.
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- Age-related changes in spermidine and association with incident heart failure. [Journal Article]Cardiovasc Res. 2026 Sep 30. [Online ahead of print]CR
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- The unforeseen twist of Sirt1 in cardiac hypertrophy. [Journal Article]Cardiovasc Res. 2026 Sep 28. [Online ahead of print]CR
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- Do we know the wizard: emerging roles of nexus glia in peripheral physiology. [Journal Article]Cardiovasc Res. 2026 Sep 26. [Online ahead of print]CR
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- Spatial APD heterogeneity: new insights into the role of sinus activation time. [Journal Article]Cardiovasc Res. 2026 Sep 25. [Online ahead of print]CR
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- From one plaque to many: the coming tsunami of pan-vascular disease: bringing pan-vascular disease to the centre of cardiovascular prevention. [Journal Article]Cardiovasc Res. 2026 Sep 24; 122(13):1728-1731.CR
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- Endothelial TLR4 coordinates angiogenesis and inflammation through a CXCR2-neutrophil-oxidative axis. [Journal Article]Cardiovasc Res. 2026 Sep 24. [Online ahead of print]CR
- CONCLUSIONS: Endothelial-intrinsic TLR4 functions as a vascular inflammatory integrator that links microbial pattern recognition with endogenous oxidation-derived danger signaling to coordinate chemokine production, neutrophil recruitment, MPO-linked lipid-oxidation amplification, and angiogenesis. These findings identify endothelial TLR4 as a distinct and targetable vascular inflammatory node, functionally separable from hematopoietic TLR4, with implications for sterile inflammatory cardiovascular disease.
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- Postmortem DNA methylation profiling uncovers signatures associated with left ventricle size. [Journal Article]Cardiovasc Res. 2026 Sep 24. [Online ahead of print]CR
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- Healthy bone marrow transplantation into hypertriglyceridemic rats improves cardiac reparative fibrosis post-myocardial infarction. [Journal Article]Cardiovasc Res. 2026 Sep 23. [Online ahead of print]CR
- CONCLUSIONS: Transplantation of healthy BM into HTG animals enhances the capacity to counteract myocardial injury post-AMI and restores metabolic disturbances improving overall recovery.
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- Could defining arterial resilience identify protective factors for vascular ageing? [Journal Article]Cardiovasc Res. 2026 Sep 22. [Online ahead of print]CR
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- Vitamin D in coronary heart disease: a Mendelian randomization meta-analysis of data stratified by 25(OH)D levels. [Journal Article]Cardiovasc Res. 2026 Sep 22. [Online ahead of print]CR
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- Spatial heterogeneity of APD under long QT conditions: characterisation and relationship to sinus activation sequence. [Journal Article]Cardiovasc Res. 2026 Sep 21. [Online ahead of print]CR
- CONCLUSIONS: Ventricular sites with distinct sinus activation times exhibit different electrophysiological properties which contribute to enhanced spatial heterogeneity of APD under long QT conditions.
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- A human engineered mini-heart platform for mimicking ventricular pump function. [Journal Article]Cardiovasc Res. 2026 Sep 21. [Online ahead of print]CR
- CONCLUSIONS: We present a biomimetic, chamber-like human cardiac model with intrinsic pumping function that enables non-invasive functional assessment of cardiac hemodynamics in vitro.
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