(Caries Res[TA])
3,761 results
  • Age-specific dental caries clusters and perceived oral health over 20 years: a novel approach to DMFT index data. [Journal Article]
    Caries Res. 2026 Oct 22; :1. [Online ahead of print]Castro PHDF, Rebelo MAB, Vettore MVCR
  • CONCLUSIONS: The relationship between dental caries and perceived oral health is dynamic, age-dependent, and cluster-specific. LPA of DMFT components captured clinically meaningful heterogeneity beyond DMFT index and its components, offering a more nuanced understanding of caries severity and its impact on subjective oral health. These findings offer preliminary evidence supporting the complementary use of cluster-based approaches within dental caries indices for oral health surveillance.
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  • Diagnostic performance of ICDAS for root caries: comparison with histological reference standards. [Journal Article]
    Caries Res. 2026 Oct 09; :1. [Online ahead of print]Usuga-Vacca M, Castellanos JE, … Martignon SCR
  • CONCLUSIONS: The visual-tactile test showed substantial agreement against histological reference standards, moderate to high diagnostic performance, and moderate discriminative power. The test showed complete observed agreement for sound surfaces and high performance for identifying initial caries, whereas extensive lesions showed good rule-out ability but lower confirmatory value. These findings support the visual-tactile ICDAS root caries criteria as useful for the detection and assessment of root caries lesions.
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  • Caries Experience in Children and Adolescents With Thalassemia: A Systematic Review and Meta-Analysis. [Review]
    Caries Res. 2026 Oct 01; :1. [Online ahead of print]Roychowdhury B, Jalihal S, … Santhosh VNCR
  • CONCLUSIONS: Unadjusted analyses indicated higher mean DMFT and dmft among children and adolescents with thalassemia; however, prediction intervals crossed zero, and substantial heterogeneity and possible reporting bias, including small-study effects, limit confidence in the stability of the observed effect. The certainty of evidence was very low, precluding a stable estimate of the magnitude of the association. Most evidence concerned transfusion-dependent children and adolescents with β-thalassemia major, limiting the generalizability of findings to other forms of thalassemia. Preventive dental care remains justified on clinical and mechanistic grounds, despite the uncertainty in the quantitative evidence.
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  • A Critical Review of the Validity and Reliability of Caries Detection Methods for Non-Cavitated Lesions. [Review]
    Caries Res. 2026 Sep 25; :1. [Online ahead of print]Murukutla S, Ismail ACR
  • CONCLUSIONS: Twenty in vivo studies from 1997 to 2025 were analyzed, focusing on clinical-visual examination, radiographs, tactile examination, and fiber-optic transillumination (FOTI), along with new adjunctive technologies, such as LumiCare, CALCIVIS, and BlueCheck. Diagnostic validity among the studies was assessed using reference standards, including histological validation, operative intervention involving fissure opening, and, in some studies, clinical-visual examination. Of the 20 included studies, 18 evaluated conventional diagnostic methods, with only two assessing tactile examination, and one evaluating FOTI. Only one study evaluated newer adjunctive technologies, including LumiCare and CALCIVIS. Visual examination with International Caries Detection and Assessment System (ICDAS) showed high sensitivity for enamel caries (up to 98%), while radiographs demonstrated greater specificity, particularly for dentinal lesions. Approximal detection with either visual or radiograph examinations showed variable sensitivity but consistently high specificity. Visual methods demonstrated moderate-to-high reliability (≥0.85), whereas radiographic reliability varied widely (0.08-1.00). Evidence for FOTI and tactile examination was limited, and the validity of FOTI remains underexplored. Despite limited available evidence, LumiCare and CALCIVIS reported high sensitivity (91-92%) and specificity (98-100%) for early caries detection.Overall, detailed visual examination demonstrated higher sensitivity, while radiographs offer greater specificity, highlighting the need for combined diagnostic approaches based on lesion type and location. Evidence for LumiCare and CALCIVIS is limited, with a need for further clinical validation.
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  • Silver-Modified Atraumatic Restorative Treatment in Geriatric Dentistry: Rationale and Evidence Gaps for Root Caries Management. [Review]
    Caries Res. 2026 Sep 08; :1. [Online ahead of print]León S, Muñoz-Sandoval C, … Giacaman RACR
  • CONCLUSIONS: This review critically examines the biological rationale, current evidence, clinical indications, limitations, and knowledge gaps associated with SMART for root caries management in older adults. Clinical evidence supports SDF as a non-restorative option for arresting active RCLs in older populations. Because SDF alone is less invasive than SMART, it should be preferred when lesion arrest is the principal treatment objective and the lesion remains cleansable, asymptomatic, and functionally acceptable. A restorative intervention may be indicated for selected cavitated lesions when loss of anatomical contour results in persistent plaque-retentive morphology, impaired cleansability or function, or structural rehabilitation needs. However, evidence evaluating SMART derives predominantly from paediatric and laboratory studies, and its comparative effectiveness over SDF alone, ART, or other restorative approaches has not been demonstrated in older adults. The combination of SDF and high-viscosity glass-ionomer cement is, therefore, supported by mechanistic plausibility rather than geriatric clinical evidence. Important uncertainties remain regarding appropriate case selection, treatment sequencing, long-term restoration survival, subgingival performance, retreatment needs, cost-effectiveness, and patient-reported outcomes.SDF is supported by clinical evidence for arresting active RCLs in older adults and is less invasive than SMART. Many non-cavitated, shallow, or cleansable RCLs do not require restoration and may be managed using non-restorative strategies. Restoration should be considered only when an independent restorative indication exists, including persistent plaque-retentive cavitation, impaired cleansability or function, loss of anatomical contour, or structural rehabilitation needs. No clinical evidence currently demonstrates that SMART is superior to SDF alone, ART, or other restorative approaches for RCLs in older adults. SMART should, therefore, be regarded as a biologically plausible but unproven option for selected cavitated lesions, pending geriatric comparative clinical trials.
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