Unbound Prime | Circulation.

(Circulation.[TA])

63,554 results

Long-Term Effectiveness of Intensive Blood Pressure Management Led by Nonphysician Community Healthcare Providers on Cardiovascular Events: 7-Year Follow-Up of a Cluster Randomized Trial. [Journal Article]
Circulation. 2026 Aug 28. [Online ahead of print]Sun G, Guo X, … CRHCP Study GroupCirc
CONCLUSIONS: Multicomponent BP management strategy with a BP target <130/80 mm Hg led by NPCHPs achieved sustained BP control and reduced CVD risk during both the 7-year overall and 3-year posttrial periods.
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Hypertension Control Programs: A Global Call to Action. [Editorial]
Circulation. 2026 Aug 28. [Online ahead of print]Post WSCirc
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Low Ventricular Chamber Stiffness Identifies a High-Risk Eccentric Remodeling Phenotype in the Fontan Circulation: A FORCE Registry Analysis. [Journal Article]
Circulation. 2026 Aug 28. [Online ahead of print]Van den Eynde J, Van De Bruaene A, … FORCE InvestigatorsCirc
CONCLUSIONS: Contrary to prevailing assumptions, lower rather than higher chamber stiffness was associated with adverse Fontan outcomes, identifying a high-compliance phenotype characterized by ventricular dilation and eccentric remodeling. These findings suggest that, in the contemporary FORCE cohort, Fontan failure might be more closely associated with this remodeling phenotype than with progressive stiffening.
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Global Efficacy of Aficamten in Nonobstructive Hypertrophic Cardiomyopathy: Results From ACACIA-HCM. [Journal Article]
Circulation. 2026 Aug 28. [Online ahead of print]Maron MS, Masri A, … ACACIA-HCM InvestigatorsCirc
CONCLUSIONS: In patients with nHCM, aficamten was associated with improvements across a broad range of clinically relevant measures including symptom burden and diastolic function. These results underscore a potential benefit of aficamten in the population of patients with nHCM.
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Coronary Artery Calcium (CAC): From Marker to Treatment Target? [Editorial]
Circulation. 2026 Aug 28. [Online ahead of print]Lauer MSCirc
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Vitamin K2 and D3 Supplementation in Patients With Severe Coronary Artery Calcification: The DANCODE Trial. [Journal Article]
Circulation. 2026 Aug 28. [Online ahead of print]Hasific S, Øvrehus KA, … Diederichsen ACirc
CONCLUSIONS: Among patients with severe CAC, supplementation with vitamin K2 and vitamin D3 reduced progression of CAC over 24 months. The reduction in calcification progression was not associated with an increase in noncalcified plaque volume.
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Sex Differences in Skeletal Muscle Inflammation and Dysfunction in Patients With Heart Failure and Reduced Ejection Fraction. [Journal Article]
Circ Heart Fail. 2026 Aug 27; :e014062. [Online ahead of print]Tinggaard AB, Wang J, … Wiggers HCH
CONCLUSIONS: Skeletal muscle immune cell alterations, particularly macrophage and lymphocyte imbalances, are associated with muscle dysfunction in HFrEF, exhibiting distinct sex-specific patterns. These findings demonstrate sex-specific skeletal muscle inflammation and dysfunction in HFrEF.
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