- Association between Glycoprotein Acetylation-Indicated Inflammation and Small HDL Particle Number in Coronary Artery Disease. [Journal Article]Clin Chem. 2026 Oct 15. [Online ahead of print]CC
- CONCLUSIONS: GlycA-proteins circulate freely without direct HDL binding. The empirical GlycA × s-HDL-P interaction is consistent with indirect coupling between systemic inflammation and altered lipoprotein remodeling associated with CAD risk.
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- Fragments and Ratios-The Next Wave for Cardiac Troponin Testing? [Journal Article]Clin Chem. 2026 Oct 14. [Online ahead of print]CC
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- What Should Internal Quality Control Look Like in 2030? [Journal Article]Clin Chem. 2026 Oct 14. [Online ahead of print]CC
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- Reproducible Amyloid Typing by Data-Independent Acquisition Mass Spectrometry. [Journal Article]Clin Chem. 2026 Oct 07. [Online ahead of print]CC
- CONCLUSIONS: DIA-based mass spectrometry enables reproducible peptide-level classification of amyloid deposits in FFPE tissue. Combined with standardized data processing, machine-learning classification, and rule-based peptide scoring, this approach provides a scalable framework for proteomic amyloid typing. More broadly, it may support wider adoption of mass spectrometry for peptide biomarker quantification in anatomic pathology.
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- ADLM 2026 Annual Meeting Abstracts: The Meeting of the Minds. [Conference Proceedings]Clin Chem. 2026 Oct 05; 72(10):1099-1100.CC
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- Diagnostic Challenges in γ-Heavy Chain Disease: A Case of Overestimated IgG Concentration. [Journal Article]Clin Chem. 2026 Oct 05; 72(10):1017-1022.CC
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- Mining and Refining Elusive Microproteins from Noncanonical Open Reading Frames. [Journal Article]Clin Chem. 2026 Oct 05; 72(10):1101-1103.CC
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- Commentary on Diagnostic Challenges in γ-Heavy Chain Disease: A Case of Overestimated IgG Concentration. [Journal Article]Clin Chem. 2026 Oct 05; 72(10):1022-1023.CC
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- Persistent Atypical Buprenorphine and Naloxone Metabolite Profile in Urine. [Journal Article]Clin Chem. 2026 Oct 05; 72(10):1097-1098.CC
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- Commentary on Diagnostic Challenges in γ-Heavy Chain Disease: A Case of Overestimated IgG Concentration. [Journal Article]Clin Chem. 2026 Oct 05; 72(10):1023-1024.CC
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- How to Establish a Reference Interval: A Practical Approach. [Journal Article]Clin Chem. 2026 Sep 29. [Online ahead of print]CC
- CONCLUSIONS: This paper outlines a practical approach for establishing RIs, emphasizing the selection of an appropriate reference cohort and the application of the optimal statistical techniques for both direct and indirect methods.
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- Current Evidence for Integrating Mass Spectrometry into Clinical M-Protein Assessment in Plasma Cell Dyscrasias. [Journal Article]Clin Chem. 2026 Sep 28. [Online ahead of print]CC
- CONCLUSIONS: MS-based M-protein detection represents a clinically meaningful advancement in plasma cell dyscrasias. Prospective studies with standardized work flows and direct comparison to bone marrow assays and functional imaging are required before full integration into updated response criteria.
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