(Curr Opin Cardiol[TA])
3,094 results
  • Colchicine for cardiovascular secondary prevention: evidence from recent trials and meta-analyses. [Review]
    Curr Opin Cardiol. 2026 Nov 01; 41(6):584-592.Muroke V, Samuel M, … Tardif JCCO
  • CONCLUSIONS: Low-dose colchicine has established residual inflammation as an actionable target in secondary prevention of vascular events in patients with chronic coronary disease or recent myocardial infarction. Ongoing trials will clarify colchicine's role across broader vascular indications. Future work should also focus on implementing the use of colchicine for prevention of clinical events in patients with coronary artery disease in clinical practice.
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  • Plaque vulnerability and cardiovascular risk factor burden in acute coronary syndromes: insights from optical coherence tomography. [Review]
    Curr Opin Cardiol. 2026 Nov 01; 41(6):549-555.Chmiel J, Musialek P, Jang IKCO
  • CONCLUSIONS: Current evidence supports the concept that cumulative modifiable cardiovascular risk factor burden may reflect coronary plaque biology, linking epidemiological risk assessment with imaging-defined plaque vulnerability. In this framework, cardiovascular risk factor burden may be understood as a surrogate of plaque vulnerability, linked to inflammatory, oxidative, and metabolic pathways. This association may help identify higher risk patients.
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  • Diagnostic performance and clinical impact of photon-counting detector computed tomography in coronary artery disease. [Review]
    Curr Opin Cardiol. 2026 Nov 01; 41(6):575-583.Parikh R, Shin D, … Khalique OKCO
  • CONCLUSIONS: Current evidence suggests that PCD-CT represents a transformative advancement in noninvasive coronary imaging. Beyond improving diagnostic accuracy, PCD-CT may enhance clinical decision-making, reduce unnecessary downstream testing, and expand the role of CT in comprehensive cardiovascular assessment. Future multicenter outcome studies and standardized imaging protocols will be essential to establish its long-term clinical and economic value.
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  • Strategies for increasing adoption of multiarterial coronary bypass grafting. [Review]
    Curr Opin Cardiol. 2026 Nov 01; 41(6):507-512.Leibowitz JL, Griffith BP, Brown JMCO
  • CONCLUSIONS: There is a well described late survival benefit for multiarterial bypass grafting over single arterial grafting. Recent studies support a variety of conduit choices and operative strategies to increase multiarterial bypass grafting in a safe, stepwise fashion.
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  • Statins in abdominal aortic aneurysm: a risk-benefit analysis. [Review]
    Curr Opin Cardiol. 2026 Nov 01; 41(6):556-563.Skovbo JS, Lindholt JSCO
  • CONCLUSIONS: Convergent evidence from meta-analyses, drug-wide association study, prospective dose-response cohorts, and Mendelian randomization identifies high-intensity statin therapy as a leading pharmacological candidate for slowing AAA progression. Important uncertainties remain, including the absence of randomized trials and limited evidence in women. Nevertheless, given the favourable safety profile and the near-universal cardiovascular indication in this population, current evidence supports consideration of high-intensity statin therapy in patients with AAA.
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  • What represents complete surgical myocardial revascularization in 2026? [Review]
    Curr Opin Cardiol. 2026 Nov 01; 41(6):520-525.Kim MS, Hwang SW, Kim KBCO
  • CONCLUSIONS: The concept of complete revascularization is evolving from anatomical completeness toward durable physiologic myocardial revascularization. Integration of CT-FFR and TTFM may improve surgical planning, graft assessment, and conduit durability, potentially enhancing long-term outcomes. Further randomized studies are needed to establish standardized physiology-guided CABG strategies and define their impact on long-term graft patency and survival.
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  • Key advances in secondary prevention after coronary artery bypass grafting. [Review]
    Curr Opin Cardiol. 2026 Nov 01; 41(6):526-537.Elsherbini A, Patel SK, … Verma SCO
  • CONCLUSIONS: Secondary prevention after CABG is a lifelong, multidisciplinary strategy aimed at preserving graft function, slowing disease progression, improving quality of life, and reducing recurrent cardiovascular events. Contemporary care should be individualized according to clinical phenotype, conduit strategy, comorbidity burden, thrombotic and bleeding risk, functional status, and treatment burden. Future studies should clarify persistent evidence gaps in antithrombotic therapy, cardiometabolic treatment, graft-specific outcomes, rehabilitation delivery, adherence, and patient-centered care.
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  • Coronary artery bypass grafting in women: optimizing operative outcomes. [Review]
    Curr Opin Cardiol. 2026 Nov 01; 41(6):538-548.Constantakis S, Lamarche-Silmser K, … Sozzi FBCO
  • CONCLUSIONS: Significant disparities persist across the continuum of care for women undergoing CABG, from diagnosis through long-term secondary prevention. Improving equitable implementation of evidence-based surgical strategies, increasing representation of women in randomized clinical trials, and developing sex-specific evidence are essential to optimize outcomes and inform future clinical guidelines.
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  • The role of artificial intelligence in the diagnosis of pericardial constriction. [Review]
    Curr Opin Cardiol. 2026 Sep 01; 41(5):393-399.Lipat K, Booth T, Sengupta PPCO
  • CONCLUSIONS: Applications of AI for diagnosis of constrictive pericarditis are being studied across multiple imaging modalities, but remain in early stages of development. Emerging AI concepts, including multimodal LLMs and foundation models leveraging transfer learning, show promise for further advances and eventual meaningful implementation. Cardiac CT, though underrepresented in the current AI literature for constrictive pericarditis, represents an important target for future investigation given its established role in surgical planning.
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  • Contemporary evidence for multiarterial grafting in coronary artery bypass surgery. [Review]
    Curr Opin Cardiol. 2026 Sep 01; 41(5):414-421.Sun C, Lee GS, Fremes SECO
  • CONCLUSIONS: MAG is supported by observational data, but uncertainty persists due to limited randomized evidence and variability in clinical adoption. The results of ROMA will clarify the role of MAG and help determine whether this should become the default strategy for CABG in select patients.
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  • Artificial intelligence for the assessment of diastolic function. [Review]
    Curr Opin Cardiol. 2026 Sep 01; 41(5):384-392.Tsang TSM, Yeung DFCO
  • CONCLUSIONS: Current guideline-based approaches integrate multiple Doppler, structural, and hemodynamic variables to classify diastolic function. Although these algorithms have improved standardization, they remain limited by interobserver variability, discordant parameters, indeterminate classifications, incomplete datasets, and reduced applicability in complex clinical settings. Machine learning and deep learning approaches can integrate multidimensional echocardiographic features, electrocardiographic signals, and clinical variables to identify latent physiologic patterns beyond conventional rule-based algorithms. Future work will focus on addressing limitations of AI including explainability, generalizability, regulatory considerations, and integration into clinical workflows.
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