(Drug Dev Ind Pharm[TA])
4,612 results
  • In vitro release kinetics and mathematical modeling of ribes nigrum extract-loaded PLGA/chitosan nanoparticles. [Journal Article]
    Drug Dev Ind Pharm. 2026 Oct 10; :1-16. [Online ahead of print]Karaduman E, Uygunoz D, … Moroydor Derun EDD
  • CONCLUSIONS: These findings demonstrate the value of comprehensive kinetic modeling in the design of nanoparticulate delivery systems and indicate that RN-loaded hybrid polymeric nanoparticles may be promising candidates for sustained-release mucosal delivery platforms. Further biological, stability, and in vivo studies are required to evaluate their therapeutic relevance and safety under physiologically relevant conditions.
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  • Influence of infill pattern on ketoprofen release rate from 3D printed buccal films. [Journal Article]
    Drug Dev Ind Pharm. 2026 Oct 03; :1-14. [Online ahead of print]Čanji Panić J, Todorović N, … Lalić-Popović MDD
  • CONCLUSIONS: Combining filament soaking with FDM 3D printing enables fabrication of ketoprofen buccal films with sustained release. Simple infill pattern modifications effectively modulate release profiles, highlighting the potential of this accessible approach for personalized buccal drug delivery.
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  • Design buccal film for systemic delivery of insulin. [Review]
    Drug Dev Ind Pharm. 2026 Oct 05; :1-24. [Online ahead of print]Esmaeili A, Dorkoosh F, Rafieian FDD
  • CONCLUSIONS: Mucoadhesive buccal films are a promising alternative for insulin administration. Future progress will likely depend on smart, stimuli-responsive formulations, especially glucose-responsive systems, and precision manufacturing approaches such as 3D printing. Clinical translation will require improved stability, permeability, standardization, and scalable production.
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  • Emerging trends in the integration of nanotechnology and 3D printing for next-generation drug delivery systems. [Review]
    Drug Dev Ind Pharm. 2026 Sep 20; :1-28. [Online ahead of print]Ghosh D, Jigneshkumar PN, Soman SDD
  • CONCLUSIONS: 3D printing is rapidly advancing as a transformative platform in pharmaceutical manufacturing. Continued advancements in material science, printing precision, artificial intelligence-driven design, and regulatory harmonization are expected to overcome existing limitations, enabling the development of safer, more effective, and highly customized therapeutic solutions.
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  • Darwinian nanomedicine: artificial intelligence-driven evolutionary drug delivery for adaptive and precision therapeutics. [Review]
    Drug Dev Ind Pharm. 2026 Sep 08; :1-20. [Online ahead of print]Belkare CK, Daware OVDD
  • CONCLUSIONS: Darwinian nanomedicine represents a paradigm shift from static nanoparticle design toward AI-guided adaptive optimization of drug delivery systems. Importantly, the evolutionary processes described in the framework are computationally inspired rather than biological, relying on iterative engineering and experimental optimization instead of nanoparticle self-replication or genetic inheritance. Although significant challenges remain regarding scalability, reproducibility, data standardization, manufacturing, and regulatory approval, continued advances in nanotechnology and artificial intelligence may facilitate the future translation of this framework into precision medicine applications.
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