(Dtsch Arztebl Int[TA])
5,185 results
  • Indications for Dose Adjustment of Thyroid Hormones in Older Patients. [Review]
    Dtsch Arztebl Int. 2026 Nov 13; 123(23). [Online ahead of print]Bojunga J, Koehler VF, … Denkinger MDA
  • CONCLUSIONS: While overt hypothyroidism and hyperthyroidism must be treated at any age, the need to treat subclinical hypothyroidism should be individually assessed; subclinical hyperthyroidism, by contrast, generally warrants treatment given its associated risks. In view of the risks of inadequately treated hyperthyroidism and excessively dosed levothyroxine, physicians should regularly review the indication for treatment, the dosage, and the possibility of lowering the dose or discontinuing the drug.
  • Polygenic Risk Scores: Towards Clinical Application. [Review]
    Dtsch Arztebl Int. 2026 Oct 30; 123(22). [Online ahead of print]Schumacher J, Koch V, … Nöthen MMDA
  • CONCLUSIONS: As genetic data continue to grow, the predictive value of PRS is expected to increase further. PRS are therefore likely to become an integral component of risk prediction in preventive and precision medicine.