(Epilepsy Res[TA])
5,480 results
  • Concordance between magnetoencephalography and intracranial EEG and association with surgical outcomes in MRI-negative epilepsy. [Journal Article]
    Epilepsy Res. 2026 Oct 28; 228:107952. [Online ahead of print]Pandya V, LaRocque JJ, … Raghavan MER
  • CONCLUSIONS: MEG identified localizing interictal abnormalities in approximately two-thirds of this selected cohort of patients with MRI-negative DRE. When MEG was localizing and an iEEG-defined SOZ was identified, lobar-level concordance was common. Because MEG could inform invasive evaluation, these findings reflect concordance within an MEG-informed clinical workflow rather than independent validation against iEEG. Surgical outcome and histopathology associations were exploratory and will need to be validated in larger cohorts.
  • Cannabidiol in pediatric drug-resistant epilepsies: A systematic review and meta-analysis of seizure responder rates and neurobehavioral outcome reporting. [Review]
    Epilepsy Res. 2026 Oct 15; 228:107935. [Online ahead of print]Praticò ADER
  • CONCLUSIONS: Approximately half of children with drug-resistant epilepsies treated with adjunctive cannabidiol achieve a ≥ 50% seizure reduction in the available, predominantly observational literature; randomized trials suggest a somewhat lower proportion, and long-term estimates are likely inflated by selective retention. The literature remains strongly seizure-centered, while cognitive and behavioral outcomes are inconsistently assessed and poorly standardized. Future pediatric CBD studies should incorporate harmonized longitudinal follow-up and standardized neurodevelopmental outcome measures alongside seizure outcomes.
  • Efficacy of Lactobacillus reuteri as an adjunctive therapy for seizure control and quality of life in pediatric drug-resistant epilepsy: A prospective interventional study. [Journal Article]
    Epilepsy Res. 2026 Oct 15; 228:107936. [Online ahead of print]Abbasi E, Ghazavi A, … Rasouli JER
  • CONCLUSIONS: In this single-arm before-after study, statistically significant within-participant changes in HRQOL and seizure frequency were observed during the 12-week period following adjunctive L. reuteri supplementation. However, the absolute magnitude of these changes was modest and their clinical significance remains uncertain. Because there was no concurrent placebo control group, the observed changes cannot be attributed specifically to L. reuteri supplementation. Larger, adequately powered placebo-controlled randomized trials are needed to determine whether L. reuteri provides a clinically meaningful benefit in pediatric drug-resistant epilepsy.
  • Response to: "Early benzodiazepine treatment and electrographic seizures after febrile status epilepticus". [Letter]
    Epilepsy Res. 2026 Oct 06; :107931. [Online ahead of print]Souma K, Yamaguchi H, … Nishiyama MER
  • We appreciate Inui et al.'s comments regarding the divergent prognostic outcomes of patients with electrographic seizures (ESz) between our studies. The poorer prognosis in their cohort compared to ours likely stems from three key differences. First, baseline disease severity significantly differed. Our cohort predominantly consisted of milder cases, such as febrile seizures, with only 17.2% requ…
  • Impact of Ramadan on seizure-related emergency department visits in Qatar. [Journal Article]
    Epilepsy Res. 2026 Sep 29; 228:107929. [Online ahead of print]Zammar K, Rizwan H, … Haddad NER
  • CONCLUSIONS: Ramadan was not associated with increased seizure-related ED burden. Emergency physicians modified acute management for fasting subjects by favouring intravenous antiseizure medication loading and deferring new oral regimen initiation.