- Current aspects in surgical treatment of advanced heart failure with future durable mechanical circulatory support. [Review]Eur Surg Res. 2026 Oct 23; :1. [Online ahead of print]ES
- Background Cardiovascular disease remains the leading cause of death worldwide, resulting in an increasing demand for long-term treatment options for patients with end-stage heart failure. While heart transplantation is the gold standard, donor organ shortage continues to be a major limitation, particularly in countries with opt-in consent systems. Summary Durable mechanical circulatory support (…
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- Dialyzers Outperform Activated Charcoal Filters for Extracorporeal Cisplatin Removal in an Isolated Perfused Porcine Liver Model. [Journal Article]Eur Surg Res. 2026 Oct 13; :1. [Online ahead of print]ES
- CONCLUSIONS: Hemodialysis filters improve cisplatin removal without affecting liver injury markers or blood cell counts in this experimental model.
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- A non-invasive artificial intelligence model to predict the severity of intrapancreatic perineural invasion. [Journal Article]Eur Surg Res. 2026 Sep 30; :1. [Online ahead of print]ES
- CONCLUSIONS: NI severity score >10.5 predicted poor PDAC prognosis, and AI was an useful tool to predict it.
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- Associated Radiofrequency Ablation and Portal Vein Ligation for Staged Hepatectomy Compared to Portal Vein Ligation Induces Prolonged and Enhanced Liver Regenerative Response. [Journal Article]
- CONCLUSIONS: ARAPS may enhance the proliferative response of the FLR compared to PVL alone, while still maintaining liver function comparable to PVL.
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- Temporary Mechanical Circulatory Support. [Review]Eur Surg Res. 2026; 67(1):122-127.ES
- CONCLUSIONS: Temporary mechanical circulatory support (tMCS) provides rapid hemodynamic stabilization, augments end-organ perfusion, and enables time for revascularization, recovery, durable left ventricular assist device (LVAD) implantation, or transplantation. The major tMCS modalities used in current practice include intra-aortic balloon pump, percutaneous microaxial flow pumps, left atrial-to-arterial bypass devices, and venoarterial extracorporeal membrane oxygenation (VA-ECMO), with dedicated right-sided support strategies for right ventricular failure. Selection should be driven by (i) shock stage and trajectory, (ii) dominant ventricular lesion (LV, RV, or biventricular), (iii) oxygenation need, (iv) anatomical constraints and access options, and (v) intent (bridge to decision, recovery, durable LVAD, or transplant). Randomized evidence supports immediate culprit lesion revascularization for myocardial AMI-CS and suggests benefit from routine microaxial flow pump support in carefully selected AMI-CS patients without major hypoxic brain injury risk, albeit at the cost of higher bleeding and limb ischemia. In contrast, routine early VA-ECMO in infarct-related CS has not demonstrated mortality benefit in randomized trials and is associated with increased complications; therefore, VA-ECMO should be reserved for selected phenotypes, including refractory shock with severe hypoxemia, profound biventricular failure, or circulatory collapse, and should be embedded within an explicit unloading, anticoagulation, limb perfusion, and weaning protocol.tMCS implantation and management should be based on cardiogenic severity and phenotype.
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- Two-Stage Fixation in a Rat Model of the Induced Membrane: A Novel Surgical Technique. [Journal Article]Eur Surg Res. 2026; 67(1):117-121.ES
- CONCLUSIONS: This is the first reproducible animal model of IMT incorporating a staged change in osteosynthesis, closely mimicking clinical management of chronic bone wounds. The technique offers a robust preclinical platform for studying the influence of fixation methods on membrane properties and bone healing. It is particularly relevant for translational research in wound-associated bone defects and infection control.
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- Does Treatment of Jaundice Matter before Pancreaticoduodenectomy? Results from an International Multicentre Recurrence after Whipple (RAW) Study. [Multicenter Study]Eur Surg Res. 2026; 67(1):107-116.ES
- CONCLUSIONS: We observed a nonsignificant trend towards reduced perioperative complications and improved disease-free survival following PBD prior to PD.
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- The Application of Platysma Myocutaneous Flap in Tracheostomy after Total Laryngectomy: A Novel Surgical Technique. [Journal Article]Eur Surg Res. 2026; 67(1):92-98.ES
- CONCLUSIONS: This technique is easily reproducible and suitable for patients with lower incidence of tracheal stenosis and higher satisfaction.
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- New Perfusion and Preservation Strategies for Donor Hearts. [Review]Eur Surg Res. 2026; 67(1):99-106.ES
- CONCLUSIONS: Recent preservation strategies aim to extend ischemic tolerance. This has been demonstrated for both modified hypothermic systems (e.g., SherpaPak, VitalPack) and machine perfusion devices (e.g., OCS, XVIVO). Beyond clinical performance, system selection is strongly influenced by economic factors. While conventional hypothermic storage is fully reimbursed, the substantially higher costs of advanced systems are typically covered only within the framework of clinical studies or must be financed by transplant centers.Hypothermic storage remains the standard method with proven long-term reliability, but is limited by restricted ischemic time. Novel preservation technologies extend ischemic tolerance and may improve transplantation logistics; however, their widespread implementation is currently limited by high costs and restricted reimbursement.
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- Use of Human Amnion/Chorion Membrane as a Protective Barrier in Complicated Diverticulitis Patients Undergoing Colorectal Resections. [Multicenter Study]
- CONCLUSIONS: In this real-world cohort of complicated diverticulitis patients undergoing colectomy, low rates of anastomotic leak, readmission, and reoperation were observed following application of DHACM around the anastomosis. These findings suggest DHACM may be a promising adjunct to support anastomotic healing in this high-risk population. Controlled prospective studies are warranted to confirm these observations.
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- Erratum. [Published Erratum]
- The article "Exploring an Alternative Preoperative Sentinel Lymph Node Mapping Method Using a Magnetic Tracer and Magnetic Resonance Imaging for Melanoma Patients: SCARLETT Study Protocol" [Eur Surg Res 2026;67:30-37; https://doi.org/10.1159/000549828] by Aldenhoven et al. was published with the wrong open access license. The correct license of the article is CC-BY.The original article has been u…
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- Erratum. [Published Erratum]
- The article "Simultaneous Liver-Kidney Transplantation versus Liver Transplantation in End-Stage Liver Disease Patients with Kidney Dysfunction" [Eur Surg Res. 2026;67:46-55; https://doi.org/10.1159/000550008] by Bouari et al. was published with the wrong open access license. The correct license of the article is CC-BY.The original article has been updated.
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- Erratum. [Published Erratum]
- The article "Desensitization Strategies in Immunized Heart Transplant Recipients" [Eur Surg Res. 2026;67:1-9; https://doi.org/10.1159/000549669] by Goerler et al. was published with the wrong open access license. The correct license of the article is CC-BY.The original article has been updated.
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- Retraction Statement. [Journal Article]
- The authors' accepted manuscript "Is Methylene Blue a Reliable Substitute in Sentinel Lymph Node Biopsy? A Systematic Review across Oncologic Sites" [Eur Surg Res. 2025; https://doi.org/10.1159/000549037] by Saurabh Raj, Rudrakshi Mahaldar, and Shahrukh Memon has been retracted by the Publisher and the Editor on the authors' behalf.After peer review, the accepted, unedited manuscript was publishe…
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- Efficacy of Platelet-Rich Plasma and Polyvinyl Alcohol Wound Dressing in Open Wound Healing: First Results from an Experimental Rat Model. [Journal Article]
- CONCLUSIONS: The relatively small sample size, absence of a PRP-only group, and short observation period limit the generalizability of these findings. Within these constraints, the results indicate a potential synergistic role of PRP and PVA scaffolds in promoting wound repair, supporting further studies with larger cohorts and standardized PRP preparation before clinical translation.
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