Unbound Prime | Haemophilia

(Haemophilia[TA])

6,161 results

The Analysis of the FIX-inhibitor Risks Associated With the F9 Genotype in Patients With Haemophilia B Exposes the Involvement of Nonsense Mediated-decay: Argentinean and International Series. [Journal Article]
Haemophilia. 2026 Jul 20. [Online ahead of print]Ziegler BM, Abelleyro MM, … Rossetti LCH
CONCLUSIONS: Our study provides robust estimations of F9-genotype-associated FIX-inhibitor risks in HB-patients and exposed the involvement of NMD.
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Prevalence of F8 Intron 22 Inversion in Severe Haemophilia A: Molecular Insights From a Cohort of Punjab Province of Pakistan. [Journal Article]
Haemophilia. 2026 Jul 15. [Online ahead of print]Mughal MK, Mustafa G, … Mohsin SH
CONCLUSIONS: Inv22 was present in 40% of the severe HA patients, and was associated with significantly lower FVIII levels and higher ISTH-BAT scores. These findings could be helpful in planning the molecular testing programs in similar resource constrained settings.
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Symptoms, Diagnosis, and Treatment for Women and Girls With Hemophilia: A Narrative Review. [Review]
Haemophilia. 2026 Jul 12. [Online ahead of print]Hirniak S, Samuel C, … Edginton AH
CONCLUSIONS: We conclude that while important strides have been made in this area in research and understanding, gaps remain. The research gaps in the differential symptom presentation when compared to men, potential efficacy and effectiveness of treatments in women as well as gender based behavioral difference are crucial to improving care and mitigating barriers for this cohort.
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Smartphone-Based Teledentistry to Support Clinical Triage and Risk-Informed Dental Care in Patients With Inherited Bleeding and Haemoglobin Disorders: A Cross-Sectional Diagnostic Agreement Study. [Journal Article]
Haemophilia. 2026 Jul 11. [Online ahead of print]da Silva VC, Monte CMFD, … Torres-Pereira CCH
CONCLUSIONS: Smartphone-based teledentistry demonstrated robust agreement for caries detection and meaningful capacity to support triage decisions. This approach may contribute to safer and more efficient care pathways for patients with inherited bleeding and haemoglobin disorders.
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Haemophilia Management in Natural Disasters-From Field to Consensus Report. [Journal Article]
Haemophilia. 2026 Jul 08. [Online ahead of print]Demir AM, Aytaç S, … Altunbaş MH
CONCLUSIONS: This research revealed that managing chronically ill patients during disasters requires special attention. Patients emphasized the importance of knowing their health status in times of crisis. This article serves as a resource for consensus reports that associations may prepare.
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Preimplantation Genetic Testing for Families at Risk of Haemophilia: Ten-Year Single-Centre Experience. [Journal Article]
Haemophilia. 2026 Jul 08. [Online ahead of print]Mortarino M, Garagiola I, … Peyvandi FH
CONCLUSIONS: Our experience shows that PGT-M is a valid and reliable option for couples at risk of transmitting severe genetic diseases, enabling prevention of affected pregnancies and reducing the emotional burden linked to therapeutic abortion.
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Real-World Outcomes of Prophylaxis With rIX-FP in Germany: A Prospective, Non-Interventional Study in Haemophilia B. [Journal Article]
Haemophilia. 2026 Jul 07. [Online ahead of print]Oldenburg J, Wenning S, … all study investigatorsH
CONCLUSIONS: This multicentre, non-interventional study in Germany demonstrates that rIX-FP prophylaxis is effective and well tolerated in PwHB of all ages in routine clinical practice and reinforces the results of the clinical trials.
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Prophylactic Factor Replacement Versus on-Demand Factor Replacement Following Primary Total Knee Arthroplasty in Patients With Hemophilia: A Retrospective Study With an Average 10-Year Follow-up. [Journal Article]
Haemophilia. 2026 Jul 05. [Online ahead of print]Luo Z, Zhong X, … Weng XH
CONCLUSIONS: Long-term prophylactic factor replacement after primary TKA seemed to optimize surgical outcomes and improve prosthesis survival. However, due to the limitations of this study, its conclusions should be confirmed by future, better-designed studies (prospective, double-blind, randomized).
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Accuracy of Factor VIII Assays for Measuring Damoctocog Alfa Pegol: A Comparative Analysis. [Journal Article]
Haemophilia. 2026 Jul 05. [Online ahead of print]Cluitmans JCA, Meijer P, … Stroobants AKH
CONCLUSIONS: We have evaluated accuracy results for 19 Factor VIII assays in order to provide evidence-based guidance for clinical laboratories in selecting appropriate assay methodologies for reliable quantification of the activity of Damoctocog alfa pegol. Assay performance should be locally validated as large interlaboratory variation is observed.
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Real-World Assessment of rVIII-SingleChain for Prophylactic Treatment in People With Severe Hemophilia A in High-Resource Settings. [Journal Article]
Haemophilia. 2026 Jul 05. [Online ahead of print]Weng TF, Chen SH, Chen YCH
CONCLUSIONS: rVIII-SingleChain prophylactic treatment demonstrated effective bleeding control in PwSHA in Taiwan, with low dosing frequency (≤2 times/week) in most PwSHA.
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Male Range of Motion Norms in the Haemophilia Joint Health Score Underrepresent the Severity of Joint Damage in Females. [Journal Article]
Haemophilia. 2026 Jul 03. [Online ahead of print]Barrett M, Singer-Fox L, … Warren BBH
CONCLUSIONS: Applying male ROM values to HJHS calculations in females with bleeding disorders underestimates haemarthropathy, particularly in the ankle.
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