Unbound Prime | Heart Rhythm

(Heart Rhythm[TA])

9,208 results

Clinical Implications of Adjunctive Posterior Wall Isolation According to Ablation Modality: A Subanalysis of the CORNERSTONE AF Trial. [Journal Article]
Heart Rhythm. 2026 Sep 24. [Online ahead of print]Miyazaki S, Nitta J, … Sasano THR
CONCLUSIONS: Adjunctive LAPWI did not significantly improve freedom from atrial arrhythmia with either ablation modality, with no significant treatment-by-modality interaction. The potentially favorable findings with LAPWI after cryoballoon PVI should be considered exploratory and hypothesis-generating.
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Atrial Fibrillation Cycle Length Dynamics During Pulmonary Vein Isolation and Posterior Wall Pulsed Field Ablation. [Journal Article]
Heart Rhythm. 2026 Sep 24. [Online ahead of print]Bianchini L, Schiavone M, … Tondo CHR
CONCLUSIONS: Post-PVI fast LAPW activity does not predict recurrence after LAPWA in PersAF patients. CS-CL prolongation >23.5% after LAPWA may serve as a useful real-time marker of effective substrate modification and arrhythmia control.
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Catheter ablation for atrial fibrillation in very young adults - multicentric data from the AF-YOUNG registry. [Journal Article]
Heart Rhythm. 2026 Sep 24. [Online ahead of print]Doldi F, Pavel F, … Eckardt LHR
CONCLUSIONS: In adults below 30 years, catheter ablation for atrial fibrillation delivers high rhythm control with low complication rates. Benefit is lower in persistent than paroxysmal atrial fibrillation. Atrial fibrillation subtype is the strongest determinant which may argue for early referral to ablation as first-line rhythm control in young adults.
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Anatomical Approach from Aortic Sinus of Valsalva for Para-Hisian Premature Ventricular Contractions: Safety and Outcomes. [Journal Article]
Heart Rhythm. 2026 Sep 24. [Online ahead of print]Sugawara M, Sroubek J, … Higuchi KHR
CONCLUSIONS: Coronary cusp ablation incorporated into a stepwise, multi-site ablation strategy may be associated with better procedural outcomes for para-Hisian PVC ablation without compromising safety. Earlier activation and close anatomical proximity between the para-Hisian site and the cusp region predict successful ablation using this approach.
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Preclinical Impact of New Variable Loop Circular Catheter Waveform. [Journal Article]
Heart Rhythm. 2026 Sep 24. [Online ahead of print]Di Biase L, Zou F, … Zhang XDHR
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Acute Effects of Physical Exercise in Patients with Arrhythmogenic Cardiomyopathy Harbouring Plakophilin-2 Variants. [Journal Article]
Heart Rhythm. 2026 Sep 24. [Online ahead of print]Beltrami FG, Boyle KGPJM, … Saguner AMHR
CONCLUSIONS: Early recovery monitoring is essential to properly assess the arrhythmic burden of exercise in PKP-2 ARVC. Small muscle mass exercises showed the lowest PVC burden and cardiac load - surrogate markers of arrhythmic risk and disease progression - and therefore offer a promising path for prescribing exercise in this population. Exercise intensity guidelines for ARVC are insufficiently clear and should be refined.
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Peri-Procedural Ischemic Stroke in Patients Undergoing Ventricular Tachycardia Ablation: Incidence, Predictors, and Impact on Mortality. [Journal Article]
Heart Rhythm. 2026 Sep 23. [Online ahead of print]Agrawal A, Bhagat U, … Santangeli PHR
CONCLUSIONS: In this large real-world cohort, P-IS following VT ablation occurred in approximately 3% of patients and was associated with a marked increase in in-hospital mortality. Risk was further amplified by cardiovascular comorbidities and indicators of critical illness. These findings underscore the need for dedicated studies evaluating strategies to mitigate P-IS risk in patients undergoing VT ablation.
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Quantitative CT Lead Localization Reveals Proximal Left Bundle Targeting Facilitates Superior Physiologic Pacing. [Journal Article]
Heart Rhythm. 2026 Sep 20. [Online ahead of print]Ponnusamy SS, Spaziani S, … Vijayaraman PHR
CONCLUSIONS: In this proof-of-concept anatomic study, a two-measurement rule classified CSP lead position objectively. Near-native paced activation requires proximal targeting (LH ≤ 25 mm), which neither the procedural label nor ECG can identify - quantitative imaging is required.
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Non-Invasive Median Nerve Stimulation with a Wearable Stimulator to Reduce Atrial Arrhythmia Recurrence after Atrial Fibrillation Ablation: The NEUROPULSE Pilot. [Journal Article]
Heart Rhythm. 2026 Sep 20. [Online ahead of print]Reddy VY, Nair DG, … Chorin EHR
CONCLUSIONS: Wearable MNS after AF ablation was associated with fewer recurrent atrial arrhythmia events. This pilot study warrants confirmation in an adequately-powered trial.
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STAR Apollo™ Map-Guided Redo Ablation for Recurrent Persistent Atrial Fibrillation after Prior Pulmonary Vein Isolation: Procedural Feasibility, Safety, and Twelve-Month Rhythm Outcomes from a Prospective Multicenter Study (NCT05826665). [Journal Article]
Heart Rhythm. 2026 Sep 20. [Online ahead of print]Kabra R, McKillop M, … STAR Apollo Study InvestigatorsHR
CONCLUSIONS: In recurrent persistent AF after prior PVI, STAR Apollo-guided redo ablation was feasible and safe, added a modest mapping step, and was associated with sinus rhythm and symptom improvement in most patients at 12 months. Designed as a feasibility and safety study, and being single-arm, these data cannot establish the incremental efficacy of STAR guidance; the encouraging rhythm outcomes are hypothesis-generating and support a randomized comparison with PV re-isolation alone.
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Integrated Hemodynamic Sensing, Electrical Sensing, and Ventricular Pacing from a Novel Substernal Lead: An Acute Human Study. [Journal Article]
Heart Rhythm. 2026 Sep 20. [Online ahead of print]Cai C, Gu K, … Chen MHR
CONCLUSIONS: Acute placement of this multifunctional substernal lead was feasible and enabled integrated hemodynamic and electrical sensing with acute ventricular capture. These findings provide preliminary human support for further development of physiology-guided extravascular ICD systems; chronic performance and clinical validation of the hemodynamic sensing algorithm require further study.
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