(Investigative ophthalmology visual science[TA])
26,110 results
  • Abnormal Binocular Rivalry Dynamics in Amblyopia: A Potential Diagnostic Marker. [Journal Article]
    Invest Ophthalmol Vis Sci. 2026 Aug 03; 67(10):66.Chopin A, Rossi A, … Levi DMIO
  • CONCLUSIONS: Binocular rivalry dynamics are fundamentally altered in amblyopia, revealing disrupted reversal mechanisms. These dynamics distinguish amblyopia from normal vision and differentiate between etiologies. The perfect separation achieved suggests that quantifying rivalry dynamics holds significant potential as a rapid noninvasive diagnostic tool.
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  • Machine Learning-Based Cytokine Endotyping of Thyroid Eye Disease. [Journal Article]
    Invest Ophthalmol Vis Sci. 2026 Aug 03; 67(10):67.Jing G, Wu X, … Fu SIO
  • CONCLUSIONS: Using machine learning, we identified a four-cytokine signature that robustly stratifies TED patients into four immunologically and clinically distinct endotypes. The CKC scoring model, derived from this signature, enables the accurate and reproducible prediction of endotype membership.
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  • Subtype-Specific Macular Microvascular Changes in Accommodative Esotropia Assessed by Optical Coherence Tomography Angiography. [Journal Article]
    Invest Ophthalmol Vis Sci. 2026 Aug 03; 67(10):68.Güven S, Bozoklu M, Arikan SIO
  • CONCLUSIONS: Children with AE exhibit significant, layer-specific microvascular alterations predominantly confined to the superior quadrant, with distinct patterns across AE subtypes. After FDR correction, CC findings in high AC/A ratio and partially accommodative subtypes, and OR findings in high AC/A ratio subtypes, remained significant. These findings suggest that chronic accommodative effort and convergence stimulation may influence retinal microvasculature, providing new insights into the pathophysiology of AE.
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  • Influence of Refractive Index of the Crystalline Lens on Optical Biometric Measurements for Cataract Patients. [Journal Article]
    Invest Ophthalmol Vis Sci. 2026 Aug 03; 67(10):61.He JC, Hoover A, … Wang JIO
  • CONCLUSIONS: The Scheimpflug imaging-equipped whole-eye OCT system provides a useful technique to measure AL and LT with the NLens determined for the cataract eye in vivo. The NLens varies substantially from individual eye to individual eye among the patients with cataract, and plays a critical role for deriving accurate AL and LT measurements. During cataract surgery the accurate AL and LT measurements should be used for IOL power calculation.
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  • Orientation-Specific Inhibitory Plasticity in Binocular Rivalry. [Journal Article]
    Invest Ophthalmol Vis Sci. 2026 Aug 03; 67(10):64.Huang C, Chen Z, … Cai YIO
  • CONCLUSIONS: These findings suggest that rivalry-induced plasticity may arise from orientation-specific weakening of interocular suppression, mediated by anti-Hebbian plasticity at inhibitory synapses. This work provides a mechanistic framework for understanding experience-dependent short-term binocular plasticity in the adult visual system.
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  • How "Micro" Is Microperimetry? Characterizing the Effect of Fundus Tracking on the Psychometric Function. [Journal Article]
    Invest Ophthalmol Vis Sci. 2026 Aug 03; 67(10):55.Lipsky T, Ehrenzeller C, … Pfau MIO
  • CONCLUSIONS: Even in healthy volunteers with stable fixation, fundus tracking measurably lowered apparent sensitivity at "non-seeing" loci (i.e., reduced spurious responses inside the blind spot) and steepened FoS curves in the "seeing" retina. A criterion intensity in the range of 10 to 16 dB is a defensible choice for separating "seeing" and "non-seeing" retina in suprathreshold (defect-mapping) perimetry paradigms.
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