- The association between parental health numeracy and medication adherence among children with asthma in Jordan: A cross-sectional study. [Journal Article]J Asthma. 2026 Oct 22; :1-21. [Online ahead of print]JA
- Introduction: Parental health numeracy is relevant to pediatric asthma management because caregivers often interpret medication quantities, risk information, and peak-flow thresholds. Objective: This study examined the adjusted association between parental health numeracy and medication adherence among children with asthma in Jordan. Methods: A cross-sectional study was conducted with 400 parents…
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- The Effect of Nasal Corticosteroids and Antihistamines on Asthma Control in Patients with Asthma and Comorbid Allergic Rhinitis: A Systematic Review. [Review]J Asthma. 2026 Oct 21; :1-24. [Online ahead of print]JA
- CONCLUSIONS: Adjunctive treatment of AR with antihistamines or INCS, shows a clinically relevant improvement in asthma symptom control among adults with asthma. However, the evidence base is constrained by small sample sizes, short follow-up periods, and suboptimal reporting. More Powered clinical trials using standardized asthma metrics are needed to clarify the long-term benefit and cost-effectiveness.
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- Association Between Serum Magnesium Status and Bronchial Asthma Severity: A Gender-Matched Retrospective Cohort Study. [Journal Article]J Asthma. 2026 Oct 21; :1-14. [Online ahead of print]JA
- CONCLUSIONS: Hypomagnesaemia was strongly associated with greater asthma severity in this cohort, and the study hypothesis was supported in this sample. Because exposure and outcome were ascertained contemporaneously from retrospective records, these data cannot establish whether hypomagnesaemia contributes to severe asthma, arises as a consequence of severe disease or its treatment, or reflects a shared cause. The wide confidence intervals reflect sparse data in the extreme severity categories. These findings are hypothesis-generating and do not support a change in current practice; prospective studies with serial magnesium measurement and adjustment for treatment, renal, and nutritional confounders are required.
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- Planned biologic discontinuation in severe asthma: a systematic review and meta-analysis. [Review]J Asthma. 2026 Oct 22; :1-15. [Online ahead of print]JA
- CONCLUSIONS: Biologic discontinuation in severe asthma carries a moderate-certainty increased exacerbation risk. Because universal de-escalation criteria cannot yet be defined, decisions should be individualized, guided by eosinophil count, exacerbation history, remission duration, and biomarker trajectory, until prospective trial data become available.
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- Usability, educational engagement, and patient-reported outcomes in a mobile asthma intervention. [Journal Article]J Asthma. 2026 Oct 20; :1-15. [Online ahead of print]JA
- CONCLUSIONS: In this urban, high-burden cohort, usability predicted early engagement but not clinical benefit. Baseline outcome status remained the strongest predictor of longitudinal outcomes. These findings suggest that digital asthma interventions may require targeted, content-specific engagement strategies beyond usability alone to improve outcomes.
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- METTL3 destabilizes RFX7 to ameliorate PDGF-BB-induced airway smooth muscle cell dysfunction and inflammation in an in vitro model of childhood asthma. [Journal Article]J Asthma. 2026 Oct 20; :1-13. [Online ahead of print]JA
- CONCLUSIONS: METTL3-mediated destabilization of RFX7 ameliorated PDGF-BB-induced ASMC proliferation, migration, and invasion, while simultaneously suppressing inflammation, oxidative stress, and macrophage polarization. Targeting this METTL3-RFX7 axis may offer a novel therapeutic strategy to mitigate airway remodeling and inflammation in childhood asthma.
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- Parent perspectives on the potential use of smart inhalers for asthma management in children: a qualitative interview study. [Journal Article]J Asthma. 2026 Oct 19; :1-15. [Online ahead of print]JA
- Achieving adequate adherence to preventer medication remains a challenge in the management of paediatric asthma. A minimum of 75% adherence is recommended to achieve adequate clinical control, however actual adherence rates are often lower and are influenced by the unpredictability of family life and competing demands. Smart inhalers aim to support adherence to preventer medications by monitoring…
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- Changing Patterns of Diagnostic Testing in Children With Asthma: Evidence of Redistribution, Overuse, and Recovery After the COVID-19 Pandemic. [Journal Article]J Asthma. 2026 Oct 19; :1-15. [Online ahead of print]JA
- CONCLUSIONS: Pediatric asthma diagnostic practice underwent domain-specific restructuring rather than uniform disruption, consistent with a process of diagnostic redistribution across testing domains. Post-pandemic intensification of PFT may reflect improved adherence to objective diagnostic confirmation, whereas persistent contraction in selected domains warrants continued monitoring.
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- Safety and Efficacy of Albuterol-Budesonide Versus Albuterol Alone in Asthma: A GRADE-assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials. [Review]J Asthma. 2026 Oct 19; :1-14. [Online ahead of print]JA
- CONCLUSIONS: Albuterol-budesonide significantly reduces severe asthma exacerbations and systemic corticosteroid use while improving lung function, supporting its use as an effective and safe reliever therapy in asthma management, although the small number of trials and the heterogeneity seen for some outcomes should be kept in mind.
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- Composite sleep patterns and the allergy-related composite outcome among American and Chinese older adults: exploration of depressive symptoms as a potential mediator. [Journal Article]J Asthma. 2026 Oct 23; :1-10. [Online ahead of print]JA
- CONCLUSIONS: Poor sleep was associated with heterogeneous allergy-related outcomes among US older adults, while CHARLS provided complementary longitudinal evidence for incident asthma. Depressive symptoms statistically accounted for part of the observed sleep-allergy association.
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- A Prospective Observational Real-World Study to Assess the Effectiveness and Safety of Single-Inhaler Triple Therapy with Glycopyrrolate/Formoterol Fumarate/Budesonide in Patients with Uncontrolled Asthma. [Journal Article]J Asthma. 2026 Oct 17; :1-12. [Online ahead of print]JA
- CONCLUSIONS: In routine practice, SITT BGF was associated with short-term improvements in lung function, asthma control, and QoL in adults with uncontrolled asthma. The mean ACT improved to partially controlled range at 12 weeks. Results suggest short-term effectiveness and tolerability, but longer-term and comparative studies are needed.
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- Geographic patterns of asthma morbidity: a systematic review of Sand and dust storm (SDS) impacts in Asia. [Review]J Asthma. 2026 Oct 19; :1-13. [Online ahead of print]JA
- CONCLUSIONS: SDS are a significant burden on respiratory health in Asia. Our findings underscore the need for targeted, region-specific public health strategies and improved air quality monitoring. However, results are subject to limitations, including significant study heterogeneity and potential language bias due to the exclusion of non-English publications.
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- Chronic cough in adults: a contemporary review of cough hypersensitivity syndrome and clinical management. [Review]J Asthma. 2026 Oct 07; :1-12. [Online ahead of print]JA
- CONCLUSIONS: Current evidence supports an individualized, mechanism-based approach that prioritizes identification and treatment of relevant diseases and treatable traits while recognizing cough hypersensitivity as a potential therapeutic target. Emerging peripheral neural therapies may broaden future treatment options for refractory chronic cough.
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