- Treatment Strategies and Outcomes of Aneurysms Affecting Small and Medium Arteries in Neurofibromatosis Type 1. A systematic review. [Review]J Vasc Surg. 2026 Nov 03. [Online ahead of print]JV
- CONCLUSIONS: NF1-associated aneurysms require an individualized, anatomy-driven management strategy. Endovascular therapy was the most frequently reported treatment and appears to be a viable option in anatomically suitable patients, while open and hybrid techniques remain important for selected complex lesions. However, the available evidence is derived predominantly from case reports and small case series and does not permit comparative assessment of treatment strategies. Lifelong imaging surveillance is mandatory due to the risk of recurrence and new aneurysm formation.
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- Contralateral Major Amputation Following Diabetes- and Peripheral Artery Disease-Related Limb Loss: A Systematic Review and Pooled Meta-Analysis. [Review]J Vasc Surg. 2026 Oct 30. [Online ahead of print]JV
- CONCLUSIONS: NIL major amputation remains a persistent risk in PAD and DM-related limb disease. These findings support the need for structured bilateral limb surveillance and early NIL risk stratification to inform comprehensive limb preservation care.
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- Index Below-Knee Endovascular Intervention for Intermittent Claudication Is Associated with Increased Amputation Risk. [Journal Article]J Vasc Surg. 2026 Oct 30. [Online ahead of print]JV
- CONCLUSIONS: Index below-knee intervention for IC portends greater risk of progression to CLTI, repeat PVI, and ipsilateral amputation, highlighting the potentially dangerous treatment trap of infrapopliteal intervention in patients with intermittent claudicants.
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- GLP-1 Receptor Agonists Decrease the Rate of Rupture, Cardiac Events, and Death in Patients with Abdominal Aortic Aneurysms. [Journal Article]J Vasc Surg. 2026 Oct 29. [Online ahead of print]JV
- CONCLUSIONS: The use of GLP-1RA in patients with AAA is associated with fewer ruptures, elective repairs, and improved rates of MACE and death. A prospective analysis may further elucidate if GLP-1RA should be prescribed to reduce the rate of aneurysm growth.
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- Intraoperative Estimated Blood Loss and Perioperative Transfusion are Independently Associated with Postoperative Morbidity and Mortality After Lower Extremity Bypass. [Journal Article]J Vasc Surg. 2026 Oct 28. [Online ahead of print]JV
- CONCLUSIONS: In patients undergoing LEB for CLTI, intraoperative EBL and perioperative pRBC transfusion were both independently and jointly associated with increased postoperative morbidity and mortality. These findings identify EBL and transfusion as markers of perioperative risk and support further investigation of blood-sparing strategies and individualized transfusion practices.
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- Carotid Endarterectomy Versus Trans-Carotid Artery Revascularisation (TCAR) for Asymptomatic Carotid Stenosis A Systematic Review and Meta-Analysis. [Review]J Vasc Surg. 2026 Oct 28. [Online ahead of print]JV
- CONCLUSIONS: Our results suggest that there are no significant differences between CEA and TCAR for the treatment of asymptomatic patients who require a surgical or interventional approach. Further studies are necessary to provide more robust data in this field.
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- Vascular Surgery is Overrepresented by Multiple Medical Societies Compared to its Peers. [Journal Article]J Vasc Surg. 2026 Oct 28. [Online ahead of print]JV
- Medical societies play an important role in representing physicians and their interests. Our objective was to compare the number, size, and fiscal strength of vascular societies compared to other cardiovascular specialties. All information was found via a systematic Internet search and with publicly available data (i.e. www.aamc.org). Medical societies representing vascular surgery (VS), cardiolo…
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- Ultrasound-guided selective nerve block promotes perioperative vascular remodeling and early maturation of radiocephalic arteriovenous fistulas. [Journal Article]J Vasc Surg. 2026 Oct 28. [Online ahead of print]JV
- CONCLUSIONS: Ultrasound-guided selective nerve block promotes perioperative vascular remodeling, increases postoperative blood flow, and independently facilitates early AVF maturation after radiocephalic AVF creation. These findings support SNB as a promising perioperative strategy to optimize vascular access outcomes in patients undergoing AVF creation.
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- Long-term outcomes of cyanoacrylate closure alone versus combined high saphenous ligation and cyanoacrylate closure in large-diameter great saphenous veins. [Journal Article]J Vasc Surg Venous Lymphat Disord. 2026 Oct 28; :102649. [Online ahead of print]JV
- CONCLUSIONS: In large-diameter GSVs, HSL + CAC was associated with better long-term anatomic and clinical outcomes than CAC alone, without an appreciable increase in complications. These findings suggest that adding HSL to CAC may improve long-term outcomes in selected patients with large-diameter GSVs.
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- Long-term patency outcomes after first autogenous arteriovenous fistula creation in patients aged 80 years or older: a competing-risk analysis. [Journal Article]J Vasc Surg. 2026 Oct 27. [Online ahead of print]JV
- CONCLUSIONS: Among patients selected for autogenous AVF creation, age ≥80 years was not independently associated with primary patency loss, whereas a continuous-age sensitivity analysis suggested a modest increase in risk per decade. These findings suggest that an age threshold alone should not determine AVF candidacy in otherwise suitable patients, although interpretation is tempered by loss to follow-up.
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- Insulin Dependence Erodes the Cardiac and Survival Advantage of Asymptomatic Status After Carotid Revascularization. [Journal Article]J Vasc Surg. 2026 Oct 27. [Online ahead of print]JV
- CONCLUSIONS: Insulin-dependent, diabetes was independently associated with substantially elevated odds of MI, ipsilateral stroke, mortality, and MACE after carotid revascularization, with risk sustained at 1 year. For cardiac and survival endpoints, asymptomatic patients with IDDM occupied a risk stratum comparable to symptomatic patients without diabetes. Asymptomatic status may therefore not confer the same composite risk advantage in insulin-dependent patients, with the excess being cardiac- and survival-driven. These findings support more cautious, individualized counseling and shared decision-making for asymptomatic patients with IDDM and identify insulin dependence as a clinically important, currently underemphasized modifier of perioperative risk.
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- Femoral Artery Access Outcomes and Technical Considerations in Vascular Ehlers-Danlos Syndrome. [Journal Article]J Vasc Surg. 2026 Oct 27. [Online ahead of print]JV
- CONCLUSIONS: Femoral artery access in VEDS requires deliberate individualized planning. In this cohort, manual compression for smaller-caliber access (<6 Fr) was associated with favorable outcomes, whereas major complications occurred predominantly following attempted percutaneous closure. Planned open exposure, despite use in procedures involving larger sheath sizes, was not associated with access-related complications and may warrant consideration in selected circumstances, including procedures requiring larger sheath sizes, known prior closure-related arterial injury, and high-risk genotypes.
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- Contemporary patterns of lower extremity revascularization for chronic limb-threatening ischemia in the United States: 2016-2022. [Journal Article]J Vasc Surg. 2026 Oct 27. [Online ahead of print]JV
- CONCLUSIONS: We provide contemporary analysis of U.S. hospitalizations for CLTI, demonstrating increasing rates following 2020. Overall, in-hospital rates of open revascularization declined in favor of nonoperative strategies corresponding with the greatest increase in alive discharges without amputations. Relative selection of endovascular strategies varied notably by sex, frailty, and clinical presentation. Our findings underscore the need for further investigation into optimal CLTI patient selection and coordinated integration of non-operative care, such as medical optimization, with revascularization strategies.
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- Update of a Living Network Meta-Analysis Comparing Non-compounded Polidocanol 1% Endovenous Microfoam (Varithena) Ablation versus Endovenous Thermal Ablation in Chronic Venous Insufficiency. [Review]J Vasc Surg Venous Lymphat Disord. 2026 Oct 26; :102648. [Online ahead of print]JV
- CONCLUSIONS: This living network meta-analysis update reinforced the original findings that polidocanol 1% endovenous microfoam is not statistically different from endovenous thermal ablation for venous closure or deep venous thrombosis in the treatment of chronic venous insufficiency, and adds new preliminary information on outcomes relevant to the patient experience. There was no evidence of a statistically significant difference between polidocanol endovenous microfoam ablation and endovenous thermal ablation for a composite of disease-specific quality of life and symptom improvement, or for ulcer healing. The living approach maintains rigor and efficiently keeps evidence current as new studies emerge.
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- Association of Completion Imaging Modalities and Carotid Endarterectomy Outcomes in the Vascular Quality Initiative. [Journal Article]J Vasc Surg. 2026 Oct 26. [Online ahead of print]JV
- CONCLUSIONS: Re-exploration and stroke outcomes after completion imaging reflect each modality's safety and efficacy in detecting significant technical defects. Duplex ultrasound demonstrated the lowest stroke rates and overall complications compared with angiography, doppler, and no imaging, suggesting its superior efficacy and safety. Doppler showed intermediate performance, while angiography carried the highest risk among patients who required re-exploration. Despite strong evidence favoring duplex, the majority of surgeons performing CEAs still rely on doppler or omit any completion imaging. Greater use of duplex ultrasound and incorporation of intraoperative duplex assessment into vascular training may improve intraoperative assessment, although further prospective evaluation is warranted.
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