- The Associations of Plasma Brain-derived Neurotrophic Factor with Macular Structure and Visual Function in Open-angle Glaucoma: A Cross-sectional Study. [Journal Article]J Glaucoma. 2026 Oct 28. [Online ahead of print]JG
- CONCLUSIONS: Plasma BDNF level differed across OAG disease stages and was associated with visual and structural parameters. Among younger patients, plasma BDNF quartile was associated with the fitted csGCCT-BCVA relationship. These cross-sectional findings do not establish temporal or causal relationships.
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- Interocular Asymmetry in Normal-Tension Glaucoma: Risk Factors for Unilateral Disease and Asymmetric Progression. [Journal Article]J Glaucoma. 2026 Oct 28. [Online ahead of print]JG
- CONCLUSIONS: Larger optic disc area and higher baseline IOP are associated with unilateral manifestation in NTG. Disc hemorrhage and less negative SE are correlated with high-risk progression in bilateral NTG.
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- Longitudinal OCT Angiography Versus Structural OCT for Predicting Visual Field Progression in Glaucoma. [Journal Article]J Glaucoma. 2026 Oct 28. [Online ahead of print]JG
- CONCLUSIONS: Vessel density loss independently predicted VF progression, whereas structural OCT thinning was not; in advanced glaucoma, vessel density loss remained associated with progression in mixed-model analyses. Formal head-to-head comparisons were not performed.
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- Development of a Corneal Biomechanical Risk Score for Visual Field Progression in Primary Open-Angle Glaucoma. [Journal Article]J Glaucoma. 2026 Oct 28. [Online ahead of print]JG
- CONCLUSIONS: This internally validated, exploratory risk score based on four corneal biomechanical parameters stratified POAG patients by risk of VF progression. Further validation is needed to determine its clinical utility.
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- Letter to the Editor: Respiratory Muscle Training and Intraocular Pressure: A Prospective Study in Individuals With Normal and High-Normal Intraocular Pressure. [Letter]J Glaucoma. 2026 Oct 28. [Online ahead of print]JG
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- Evaluating Long-Term Effectiveness and Safety of Glaucoma Surgical Innovations: A Systematic Review. [Journal Article]J Glaucoma. 2026 Oct 16. [Online ahead of print]JG
- CONCLUSIONS: Glaucoma surgical innovations appear effective over the medium term, but limited long-term follow-up and inconsistent safety reporting preclude firm conclusions about comparative effectiveness and long-term safety. Standardised reporting and prospective registries are needed.
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- Anterior Segment Ischemia and Neurotrophic Keratopathy Following Ultrasound Cycloplasty in Acute Angle-Closure Glaucoma. [Journal Article]J Glaucoma. 2026 Oct 16. [Online ahead of print]JG
- Ultrasound cycloplasty (UCP) is a minimally invasive, non-incisional glaucoma procedure that has emerged in recent years and is generally associated with few complications. We report a case of a patient with acute angle-closure glaucoma underwent UCP for IOP control. She developed iris neovascularization and neurotrophic keratopathy（NK）at postoperative week 6, followed by hypopyon, flattening of …
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- Preoperative Topical Steroid Use and Trabeculectomy Outcomes. [Journal Article]J Glaucoma. 2026 Oct 16. [Online ahead of print]JG
- CONCLUSIONS: Preoperative administration of topical steroids, compared to no steroids, was associated with higher surgical success rates, thicker bleb walls, and lower bleb wall reflectivity on AS-OCT at 1 year.
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- Trabeculectomy versus Transscleral Cyclophotocoagulation as a Primary Surgical Procedure in Glaucoma: A Multicenter Randomized Controlled Trial. [Journal Article]J Glaucoma. 2026 Oct 12. [Online ahead of print]JG
- CONCLUSIONS: Both procedures reduced IOP at 12 months as primary glaucoma surgeries. TRAB achieved lower final IOP, required fewer medications, and was associated with improved quality of life, whereas CPC required more adjunctive medication and retreatment in some eyes.
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- Evaluation and Comparison of Large Language Models in Answering Frequently Asked Patient Questions on Glaucoma. [Journal Article]J Glaucoma. 2026 Oct 12. [Online ahead of print]JG
- CONCLUSIONS: ChatGPT-o1 and DeepSeek-R1 responses were comparable, demonstrating notable limitations in accuracy. Reading levels similarly exceeded average U.S. adult literacy, posing challenges for patient comprehension. Rigorous oversight and targeted refinement of LLMs is necessary to enhance the reliability and accessibility of content for patient education in glaucoma.
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- Outcome of Secondary Glaucoma in Eyes With Uveal Melanoma A Population-Based Analysis. [Journal Article]J Glaucoma. 2026 Oct 08. [Online ahead of print]JG
- CONCLUSIONS: Most uveal melanoma eyes with secondary glaucoma and useful vision potential become normotensive with medication and cyclophotocoagulation and retain ≥20/400 vision. Most with less visual potential become pain-free without intensive medication and avoid enucleation.
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- Performance of 24-2C Visual Field Grid in Detecting Central Glaucomatous Defects: A Comparative Study with Microperimetry. [Journal Article]J Glaucoma. 2026 Oct 07. [Online ahead of print]JG
- CONCLUSIONS: 24-2C VF grid has a potential complementary role in glaucoma assessment for detecting central VF defects in glaucoma patients. Its structure-function correlation supports its use as a promising tool in routine clinical practice.
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- Comparison of Early Outcomes of PreserFlo MicroShunt, Ex-PRESS, and Trabeculectomy in Primary Open-angle Glaucoma. [Journal Article]J Glaucoma. 2026 Oct 07. [Online ahead of print]JG
- CONCLUSIONS: PFM demonstrated short-term outcomes broadly comparable to EXP and TLE, with a lower postoperative intervention burden. Longer-term prospective studies are needed.
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- Comparison of Intraocular Pressure Measurements Using iCare Rebound Tonometry and Goldmann Applanation Tonometry: A Systematic Review and Meta-Analysis. [Journal Article]J Glaucoma. 2026 Oct 07. [Online ahead of print]JG
- CONCLUSIONS: iCare tonometry had lower readings than GAT on average, but high heterogeneity and wide limits of agreement suggest that measurements are not directly interchangeable across clinical settings or individual patients.
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- Comparison of Anxiety Levels in Glaucoma Patients Undergoing Standard Automated Perimetry and Online Circular Contrast Perimetry. [Journal Article]J Glaucoma. 2026 Sep 28. [Online ahead of print]JG
- CONCLUSIONS: OCCP is associated with slightly lower anxiety while demonstrating comparable test duration. These findings support its potential as a slightly more tolerable, accessible and cost-effective alternative for monitoring and screening for glaucoma.
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