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Pirotte B, de Tullio P, Nguyen QA, et al. 
Chloro-Substituted 3-Alkylamino-4H-1,2,4-benzothiadiazine 1,1-Dioxides as ATP-Sensitive Potassium Channel Activators: Impact of the Position of the Chlorine Atom on the Aromatic Ring on Activity and Tissue Selectivity. [JOURNAL ARTICLE]
J Med Chem 2009 Nov 18.
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Verhoest PR, Proulx-Lafrance C, Corman M, et al. 
Identification of a Brain Penetrant PDE9A Inhibitor Utilizing Prospective Design and Chemical Enablement as a Rapid Lead Optimization Strategy. [JOURNAL ARTICLE]
J Med Chem 2009 Nov 17.
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Basse N, Montes M, Maréchal X, et al. 
Novel Organic Proteasome Inhibitors Identified by Virtual and in Vitro Screening. [JOURNAL ARTICLE]
J Med Chem 2009 Nov 17.
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Tulloch LB, Martini VP, Iulek J, et al. 
Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases. [JOURNAL ARTICLE]
J Med Chem 2009 Nov 16.
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Zask A, Kaplan J, Verheijen JC, et al. 
Morpholine Derivatives Greatly Enhance the Selectivity of Mammalian Target of Rapamycin (mTOR) Inhibitors. [JOURNAL ARTICLE]
J Med Chem 2009 Nov 16.
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Yu H, Zhao C, Chen Y, et al. 
DNA Loop Sequence as the Determinant for Chiral Supramolecular Compound G-Quadruplex Selectivity. [JOURNAL ARTICLE]
J Med Chem 2009 Nov 13.
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Maresca A, Temperini C, Pochet L, et al. 
Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins. [JOURNAL ARTICLE]
J Med Chem 2009 Nov 13.
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Genet C, Strehle A, Schmidt C, et al. 
Structure-Activity Relationship Study of Betulinic Acid, A Novel and Selective TGR5 Agonist, and Its Synthetic Derivatives: Potential Impact in Diabetes ( paragraph sign). [JOURNAL ARTICLE]
J Med Chem 2009 Nov 13.
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Prazeres VF, Tizón L, Otero JM, et al. 
Synthesis and Biological Evaluation of New Nanomolar Competitive Inhibitors of Helicobacter pylori Type II Dehydroquinase. Structural Details of the Role of the Aromatic Moieties with Essential Residues (double dagger). [JOURNAL ARTICLE]
J Med Chem 2009 Nov 13.
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Pratim Bose P, Chatterjee U, Nerelius C, et al. 
Poly-N-methylated Amyloid beta-Peptide (Abeta) C-Terminal Fragments Reduce Abeta Toxicity in Vitro and in Drosophila melanogaster. [JOURNAL ARTICLE]
J Med Chem 2009 Nov 5.
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