- Preparing surgery for Generation Z - Motivation and protective factors for pursuing a surgical career among medical students and early-career physicians: a cross-sectional study. [Journal Article]
- CONCLUSIONS: The potential future surgical workforce is predominantly female and largely belongs to Generation Z. Overall, participants emphasize the importance of high-quality and structured training, a respectful working environment, predictable career pathways, and working conditions that allow for a sustainable balance between professional and private life. Addressing these factors should be considered a strategic priority for professional societies, training supervisors, and clinical leaders to attract and sustainably retain qualified surgical trainees.
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- Upfront surgery vs. neoadjuvant therapy in pancreatic cancer with venous involvement: a multicenter retrospective analysis. [Multicenter Study]
- CONCLUSIONS: NAT maybe beneficial for patients with PC with venous involvement, as it might allow better patient selection for surgery and is associated with fewer major postoperative complications and better overall survival.
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- Orbitozygomatic-transsylvian approach to the insula: microsurgical anatomy and endoscopic correlation using the fiber-separation technique. [Journal Article]
- CONCLUSIONS: Endoscope-assisted OZ-TS exposure combined with a structured fiber-separation strategy provides an integrated anatomical perspective of the insular region. Early identification of vascular landmarks and systematic progression along intrinsic white matter planes facilitate anatomical definition of subcortical surgical boundaries.
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- Concordance between GPT-4 and a multidisciplinary tumor board in pancreatic cancer: A prospective pilot study. [Journal Article]
- CONCLUSIONS: GPT-4 demonstrated substantial agreement with MDT recommendations in patients with newly diagnosed or suspected pancreatic cancer. However, specific abstract prompting did not enhance the rate of concordance and GPT-4's limitations in individualized or complex contexts underscore the need for a cautious future integration into oncologic workflows.
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- Early postoperative serum IL-6 may contribute to risk stratification for pancreas-specific complications after pancreatic resection. [Journal Article]
- CONCLUSIONS: Serum IL-6 within 48 h after pancreatic resection could be useful in risk assessment for pancreas-specific complications.
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- Postoperative outcomes after inguinal hernia repair in octogenarians in Germany: an exploratory analysis of a retrospective single-centre cohort. [Journal Article]
- CONCLUSIONS: Octogenarians did not show increased postoperative morbidity. Surgical decision-making should not rely on chronological age alone.
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- Outcome after renal transplantation utilizing octogenarian donors- retrospective single-center analysis within the Eurotransplant region. [Journal Article]
- CONCLUSIONS: Following meticulous donor selection, allocating kidney grafts from donors aged 80 years or older represents a viable strategy to expand the donor pool for ESP patients.
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- Does age matter? Acute appendicitis in octogenarians vs. younger patients - results of a German multicenter analysis. [Multicenter Study]
- CONCLUSIONS: Despite a similar initial presentation, octogenarians present with more advanced appendicitis and significantly worse postoperative outcomes. This emphasizes the need for age- and comorbidity-adapted diagnostic and perioperative strategies.
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- Outcomes of living donor liver transplantation in elderly Egyptian patients: a retrospective study. [Journal Article]
- CONCLUSIONS: Living donor liver transplantation for carefully selected elderly recipients yields comparable early survival outcomes to younger recipients. However, the elderly cohort faces a significantly higher risk of early morbidity and not statistically significant lower graft survival. Rigorous selection and targeted perioperative care are therefore essential.
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- Longitudinal changes in bioelectrical impedance-derived body composition after sleeve gastrectomy in patients with class III obesity. [Journal Article]
- CONCLUSIONS: Sleeve gastrectomy was associated with marked longitudinal changes in BIA-derived estimates of body composition during the first 24 postoperative months. Besides the expected reduction in fat mass, decreases in fat-free mass and skeletal muscle mass as well as transient changes in phase angle were observed. These findings emphasize the importance of longitudinal body composition assessment following bariatric surgery. Future studies should investigate whether structured nutritional and exercise interventions may further improve postoperative body composition outcomes. Because body composition was assessed exclusively by BIA, the results should be interpreted as impedance-derived estimates rather than direct measurements of individual tissue compartments.
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- A Validated, explainable machine learning-based preoperative risk model for microvascular invasion in hepatocellular carcinoma. [Journal Article]
- CONCLUSIONS: An XGBoost model incorporating tumor diameter, AFP, GGT, and PIV exhibited robust performance in assessing preoperative MVI among HCC patients.
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- Efficacy and clinical outcomes of proximal splenic artery embolization in patients with chemotherapy induced thrombocytopenia. [Journal Article]
- CONCLUSIONS: Proximal SAE is a safe and effective treatment option in patients with CIT, with potential benefits in early re-initiation of chemotherapy. Further studies should be conducted to evaluate the longer-term effects of the procedure, further identify eligible patients, and compare to distal SAE.
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- Lithium-associated hyperparathyroidism: a systematic review of prevalence and surgical outcomes. [Systematic Review]
- CONCLUSIONS: LHPT represents a clinically significant endocrine complication characterized by heterogeneous pathological patterns. The elevated prevalence of multiglandular disease has important implications for surgical planning. Given the high proportion of multiglandular involvement, surgeons should maintain a low threshold for bilateral neck exploration, particularly in patients with prolonged lithium exposure or intraoperative findings suggestive of multiple gland involvement.
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