- Evaluation of Fundus Radiation Intensity During Femtosecond Photoemulsification Cataract Surgery. [Journal Article]Lasers Surg Med. 2026 Oct 07. [Online ahead of print]LS
- CONCLUSIONS: The measured fundus radiation power during femtosecond photoemulsification remained below the retinal safety threshold, supporting the retinal safety of this surgical mode under the tested conditions.
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- Carbon Dioxide Fractional Laser Versus Micro-Plasma Radiofrequency for Hypertrophic Scar: A Two-Center, Open-Label, Randomized, Split-Scar Study. [Journal Article]Lasers Surg Med. 2026 Oct 03. [Online ahead of print]LS
- CONCLUSIONS: Both CDFL and MPRF were effective and safe for the treatment of HS, but they improved different scar domains. CDFL produced greater improvement in scar color and vascularity by reducing vascular diameter and density, whereas MPRF led to greater improvement in scar thickness and elasticity.
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- Comparative Assessment of 532/1064-nm KTP/Nd: YAG and 595-nm Pulsed Dye Laser for Cutaneous Vascular Lesions: A Prospective Split-Site Study. [Journal Article]Lasers Surg Med. 2026 Sep 26. [Online ahead of print]LS
- CONCLUSIONS: Our findings demonstrate that both 532/1064-nm KTP/Nd: YAG and 595-nm PDL are effective in the treatment of cutaneous vascular lesions. At selected settings, subjects reported significantly less pain, redness, and purpura following KTP/Nd: YAG treatment compared to PDL.
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- Development and Characterization of Liposomes Containing a Zn(II) Porphyrin Derivative for the Application of Photodynamic Therapy in the Treatment of Breast Cancer. [Journal Article]Lasers Surg Med. 2026 Sep 24. [Online ahead of print]LS
- CONCLUSIONS: The results demonstrate that the nanostructured systems show promising performance, reinforcing the potential of stimulus-responsive therapies in the treatment of BC.
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- Institutional Variation in Laser Access, Workflow, and Safety Practices Among Urologists: A Contemporary Survey. [Journal Article]Lasers Surg Med. 2026 Sep 23. [Online ahead of print]LS
- CONCLUSIONS: This survey identified substantial respondent-reported variation in laser access, staffing requirements, and safety practices. The findings describe perceived institutional practices and barriers and do not establish effects on treatment delays, workflow efficiency, patient outcomes, or comparative safety. Future studies should directly compare institutional models using objective measures of access, workflow, treatment delays, and safety outcomes.
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- Comparison of the Clinical Effectiveness of Two Photobiomodulation Systems for Facial Nerve Dysfunction Following Temporomandibular Joint Surgery. [Journal Article]Lasers Surg Med. 2026 Sep 23. [Online ahead of print]LS
- CONCLUSIONS: Both photobiomodulation systems were associated with progressive improvement in facial nerve function following TMJ surgery. Although change-score analyses showed greater improvements in Sunnybrook and FaCE Scale scores in the GRR Laser group, linear mixed-effects model analyses did not demonstrate a significant difference in the longitudinal recovery pattern between the two treatment groups.
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- 1030-nm Ultrashort-Pulse Laser Irradiation Is Associated With a Delayed Reduction in Cellular Metabolic Activity in A549 Cells. [Journal Article]Lasers Surg Med. 2026 Sep 16. [Online ahead of print]LS
- CONCLUSIONS: Within the tested ranges, 1030-nm ultrashort-pulse laser irradiation was associated with parameter-related changes in relative CCK-8-derived metabolic activity in A549 cells. Direct cell counting under the 12.5 W/cm[2] power-density condition also showed a progressive reduction in cell number over 24 h. An empirically selected representative high-effect condition showed a comparatively large delayed reduction in metabolic activity, together with changes in Annexin V/PI-defined cell-death phenotypes and irradiation-associated transcriptomic responses. In addition, repeated DCFH-DA imaging revealed time-dependent increases in single-cell DCF fluorescence, which were reduced by NAC pretreatment. These preliminary descriptive findings provide a basis for further mechanistic investigation of ultrashort-pulse laser-cell interactions.
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- Response to Comment on "Pulsed 830-nm Laser Irradiation Modulates Aδ- and C-Fiber-Mediated Pain Thresholds in Healthy Adults: A Randomized, Sham-Controlled Trial". [Letter]Lasers Surg Med. 2026 Sep 14. [Online ahead of print]LS
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- Comment on "Pulsed 830-nm Laser Irradiation Modulates Ad- and C-Fiber-Mediated Pain Thresholds in Healthy Adults: A Randomized, Sham-Controlled Trial". [Letter]Lasers Surg Med. 2026 Sep 14. [Online ahead of print]LS
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- Early Recognition of the Gray-White Sign Prevents Scarring After Hemoporfin-Mediated Photodynamic Therapy in Pediatric Port Wine Capillary Malformations: A Case Series. [Journal Article]Lasers Surg Med. 2026 Sep 10. [Online ahead of print]LS
- CONCLUSIONS: Early post-treatment darkening or gray-white discoloration is a key indicator of high scarring risk. Early recognition of this sign, followed by prompt and active postoperative care, is essential to prevent scarring. This study provides important clinical insights into improving safety outcomes for pediatric patients with port wine CMs undergoing HMME-PDT.
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- Efficacy and Safety of Small-Spot 755 nm Picosecond Laser-Induced Optical Breakdown for Novel Photomechanical Skin Ablation in Asian Patients. [Journal Article]Lasers Surg Med. 2026 Sep 09. [Online ahead of print]LS
- CONCLUSIONS: A high-fluence, 5-mm small-spot picosecond LIOB treatment protocol suggests a favorable safety and efficacy profile for superficial skin ablation in pigmentary and photoaging-related lesions in Asian patients, with minimal adverse effects. Pigmentary lesions showed more favorable responses than non-pigmentary lesions. Selected complex photoaging cases treated with adjunctive large-spot therapy showed favorable clinical improvement, supporting further investigation of this combined approach. This technique may broaden the role of picosecond lasers from pigment clearance to overall skin rejuvenation. Prospective controlled studies are warranted to confirm these preliminary findings.
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- Er:YAG Laser Conditioning of Biofilm-Fouled Titanium Supports Osteoblast Adhesive Retention and Osteogenic Maturation: Stage-Specific Adhesion- and Osteogenesis-Related Transcriptomic Signatures. [Journal Article]Lasers Surg Med. 2026 Sep 07. [Online ahead of print]LS
- CONCLUSIONS: Within this supragingival-biofilm model, Er:YAG conditioning preserved local SLA roughness, reduced residual biofilm burden, improved apparent wettability, enhanced early osteoblast adhesive retention, and supported osteogenic maturation. Integrated qRT-PCR and RNA-seq findings indicated stage-specific extracellular matrix-, focal adhesion-, cytoskeleton-, and osteogenesis-related responses, with PI3K-Akt-mTOR representing an exploratory component of the osteogenic-phase network rather than a continuous or causal mechanism.
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- Clinical Efficacy and Histologic Correlation of a High-Powered 675-nm Non-Ablative Diode Laser for Facial Rejuvenation. [Journal Article]Lasers Surg Med. 2026 Sep 07. [Online ahead of print]LS
- CONCLUSIONS: High-powered 675-nm non-ablative diode laser treatment significantly improved objective skin texture parameters and provided clinically perceptible improvements in pigmentation and erythema, with favorable tolerability. These findings support its role as a versatile and effective modality for comprehensive facial rejuvenation.
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- Protective Effects of Er:YAG Laser and PRG Pro-Care Gel on Enamel Demineralization. [Journal Article]Lasers Surg Med. 2026 Sep 07. [Online ahead of print]LS
- CONCLUSIONS: Er:YAG laser irradiation, whether used alone or in combination with the PRG gel, promoted a significant protective effect against enamel demineralization, indicating its potential clinical application in the prevention of dental caries.
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- Report of Adverse Events Associated With Cutaneous Procedures: Update From the CAPER Registry. [Journal Article]Lasers Surg Med. 2026 Nov; 58(9):796-801.LS
- CONCLUSIONS: The CAPER registry provides valuable insight into AEs associated with cutaneous procedures and may help identify emerging safety concerns related to new devices or techniques. Broader engagement with AE reporting systems may inform best practices and improve patient safety, particularly as cutaneous procedures increasingly occur outside traditional clinical settings.
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