- Confined to Kambin's prism: MRI-based segmentation and prediction of the need for superior articular process removal in transforaminal endoscopic decompression. [Journal Article]Neurosurg Focus. 2026 Oct 01; 61(4):E12.NF
- CONCLUSIONS: MRI-based segmentation accurately identified foraminal anatomy that required foraminoplasty for access. This workflow turns a subjective intraoperative judgment into a reproducible, patient-specific geometrical assessment.
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- Comparative and qualitative analysis of endoscopic unilateral laminectomy with bilateral decompression versus interbody fusion in the treatment of grade 1 degenerative lumbar spondylolisthesis. [Journal Article]Neurosurg Focus. 2026 Oct 01; 61(4):E3.NF
- CONCLUSIONS: For grade 1 lumbar SPL, E-ULBD may provide superior recovery profiles and less clinical burden from complications compared with IBF. Nevertheless, both procedures were associated with surgical complication rates approaching 40%, whereas 60% of uncomplicated cases achieved comparable favorable outcomes. Facet violation > 10% was a significant risk factor for symptomatic SPL progression following E-ULBD.
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- Skeletal muscle-specific markers for paraspinal injury in full-endoscopic versus open microscopic lumbar spine surgery: a prospective observational study. [Journal Article]Neurosurg Focus. 2026 Oct 01; 61(4):E6.NF
- CONCLUSIONS: Full-endoscopic lumbar decompression was associated with significantly smaller postoperative increases in CK-MM and myoglobin levels compared with open microscopic surgery, indicating reduced paraspinal muscle injury with the endoscopic approach. Consistent with these biochemical findings, immediate postoperative back pain was also significantly lower in the endoscopic group, further supporting the clinical relevance of reduced paraspinal muscle trauma.
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- A digital care and outcomes network for endoscopic spine surgery: design, implementation, and early performance of a next-generation multicenter registry. [Multicenter Study]Neurosurg Focus. 2026 Oct 01; 61(4):E2.NF
- CONCLUSIONS: SPINEHealthie closes a key visibility gap in the early postoperative course after ambulatory endoscopic spine surgery by enabling remote, high-frequency measurement integrated with active care delivery. Conventional registries optimize for long-term benchmarking after traditional spine procedures; SPINEHealthie optimizes for ultra-early outpatient recovery surveillance after tissue-sparing surgery. These findings demonstrate that purpose-built digital registries can meaningfully advance quality improvement and patient safety in endoscopic spine surgery by capturing the rapid-recovery trajectories that traditional systems were not designed to assess.
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- Impact of tranexamic acid on visualization in full endoscopic spine surgery: a randomized controlled trial. [Randomized Controlled Trial]Neurosurg Focus. 2026 Oct 01; 61(4):E8.NF
- CONCLUSIONS: Endoscopic lumbar discectomy offers good or excellent intraoperative visualization in most cases. This study did not demonstrate a significant improvement in intraoperative visualization with the prophylactic administration of intravenous TXA. While TXA appeared safe, its routine use specifically to enhance visual clarity in single-level endoscopic lumbar discectomy was not currently supported by these data.
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- Effect of adrenaline-containing irrigation on visual clarity during unilateral biportal endoscopic lumbar decompression: a retrospective comparative study. [Journal Article]Neurosurg Focus. 2026 Oct 01; 61(4):E9.NF
- CONCLUSIONS: Adrenaline-containing irrigation was associated with improved visual clarity, reduced need for irrigation, and shorter operative duration without causing significant hemodynamic instability during UBELD surgery. Prospective randomized studies are required to confirm the independent effect of adrenaline while controlling for time- and procedure-related confounding factors.
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- Transforaminal endoscopic lumbar discectomy: an economically viable option for lumbar disc herniations? A hierarchical Bayesian analysis using time-driven activity-based costing. [Journal Article]Neurosurg Focus. 2026 Oct 01; 61(4):E13.NF
- CONCLUSIONS: TELD was more expensive than both open and tubular microdiscectomy, largely driven by more expensive consumables. Moreover, both modifiable and nonmodifiable factors were identified as independent drivers of cost for endoscopy. Continued refinement of technique and patient selection, along with targeted vendor negotiations to reduce consumable costs, may improve both the economic viability and overall utilization of endoscopy.
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- Development and prospective validation of a porcine simulation model for training in unilateral biportal endoscopic spine surgery. [Journal Article]Neurosurg Focus. 2026 Oct 01; 61(4):E21.NF
- CONCLUSIONS: The porcine UBE simulation model represents a cost-effective training platform with established face, content, and construct validity and produces measurable short-term improvements in simulator performance after a single structured session. This model provides a practical approach to support structured training in UBE spine surgery. Predictive validity, long-term skill retention, and whether simulation-acquired skills shorten the operative learning curve remain hypotheses for future study.
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- Interlaminar and transforaminal endoscopic lumbar discectomy: analyzing the selection of surgical approach in 426 patients. [Journal Article]Neurosurg Focus. 2026 Oct 01; 61(4):E10.NF
- CONCLUSIONS: This analysis of patient selection criteria indicated that IELD is preferred for disc herniations within the canal at L5-S1. The likelihood of utilizing IELD at L4-5 or above significantly increases when the disc herniation is located within the canal or has migrated cranially or when there is concomitant dorsal stenosis.
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- Wound dehiscence following biportal endoscopic versus microscopic spine surgery for single-level lumbar decompression: a post hoc analysis of two randomized controlled trials. [Randomized Controlled Trial]Neurosurg Focus. 2026 Oct 01; 61(4):E19.NF
- CONCLUSIONS: BESS was associated with significantly lower wound dehiscence rates compared with MSS in patients undergoing single-level lumbar decompression or discectomy. Drainage volume ≥ 100 mL may serve as a clinical indicator for enhanced wound surveillance in MSS patients. These hypothesis-generating findings warrant validation in independent cohorts.
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- Revision status and patient-reported outcomes in thoracolumbar endoscopic spine surgery: a multicenter cohort study. [Multicenter Study]Neurosurg Focus. 2026 Oct 01; 61(4):E5.NF
- CONCLUSIONS: The authors conducted a retrospective review of a large, multicenter cohort, demonstrating similar outcomes between primary and revision thoracolumbar endoscopic decompression and discectomies, as measured by the ODI and an MCID in the ODI.
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- A hypertensive response to irrigation: endoscopic repair of a ventral spinal CSF leak. [Case Reports]Neurosurg Focus. 2026 Oct 01; 61(4):E20.NF
- Spontaneous intracranial hypotension (SIH) is most commonly caused by spinal CSF leaks, with ventral dural defects frequently requiring surgical repair when conservative measures fail. Endoscopic transforaminal approaches have emerged as minimally invasive alternatives to traditional open techniques, but the physiological consequences of continuous irrigation in the presence of a dural defect rem…
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- Bimanual technique for biportal endoscopic spine surgery: technical pearls to enhance surgical performance. [Journal Article]Neurosurg Focus. 2026 Oct 01; 61(4):E22.NF
- In conventional biportal endoscopic spine surgery, active surgical manipulation is primarily performed through the working portal using the dominant hand, while the endoscopic viewing portal serves a passive role limited to visualization. Although the biportal approach provides superior optical advantages, the functional potential of the endoscopic viewing portal remains underused. The aim of thi…
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- Comparative analysis of clinical outcomes and healthcare costs following endoscopic versus open lumbar discectomy: a multidatabase study utilizing TriNetX, NIS, and NASS. [Journal Article]Neurosurg Focus. 2026 Oct 01; 61(4):E11.NF
- CONCLUSIONS: ELD demonstrates a favorable short-term complication profile and reduced long-term need for lumbar fusion compared to OLD. While outpatient ELD carries higher charges than outpatient OLD, both approaches are substantially more cost-efficient in outpatient versus inpatient settings, supporting the adoption of endoscopic techniques in ambulatory surgical environments.
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- Comparative study of biportal endoscopic and microscopic posterior cervical foraminotomy: clinical and radiological outcomes with minimum 2-year follow-up. [Journal Article]Neurosurg Focus. 2026 Oct 01; 61(4):E18.NF
- CONCLUSIONS: BE-PCF provides clinical outcomes comparable with that of microscopic PCF while significantly reducing muscle and soft tissue injury. These findings suggest that BE-PCF is a safe and effective minimally invasive alternative for the treatment of unilateral cervical radiculopathy.
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