(Open Cardiovasc Med J[TA])
287 results
  • Aortic Area as an Indicator of Subclinical Cardiovascular Disease. [Journal Article]
    Open Cardiovasc Med J. 2022; 16.Kuipers AL, Carr JJ, … Miljkovic IOC
  • CONCLUSIONS: This is the first study to test the association of aortic area measured at multiple points with subclinical CVD. We found that combined CT assessment of ascending and descending aortic area may indicate high risk of prevalent subclinical CVD elsewhere in the body independent of age, body size, and blood pressure.
  • Diminished Returns of Educational Attainment on Heart Disease among Black Americans. [Journal Article]
    Open Cardiovasc Med J. 2020; 14:5-12.Assari S, Cobb S, … Bazargan MOC
  • CONCLUSIONS: Education reduces the risk of heart disease better among non-Hispanic Whites than for Hispanics and Blacks. Therefore, we may expect a disproportionately higher than expected risk of heart disease in Hispanics and Blacks with high educational attainment. Future research should test if the presence of high levels of environmental and behavioral risk factors contribute to the high risk of heart disease in highly educated Black and Hispanic Americans. Policymakers should not reduce health inequalities to just gaps in SES because disparities are present across SES levels, with high SES Blacks and Hispanics remaining at risk of health problems.
  • Trends of Cardiovascular Disease Mortality in Relation to Population Aging in Greece (1956 - 2015). [Journal Article]
    Open Cardiovasc Med J. 2018; 12:71-79.Kollia N, Tragaki A, … Panagiotakos DOC
  • CONCLUSIONS: Population aging is a historically unprecedented event that cannot be avoided, deterred or alleviated. Its negative effects act cumulatively with the recent increases in cardiovascular mortality, especially in the light of the ongoing economic crisis which is expected to further exacerbate the existing contrasts. A possible way to successfully cope with the new demographic realities is to unlock an, up till now largely overlooked, opportunity named "healthy aging".
  • Biomarkers and Gene Polymorphisms in Members of Long- and Short-lived Families: A Longevity Study. [Journal Article]
    Open Cardiovasc Med J. 2018; 12:59-70.Kolovou V, Diakoumakou O, … Kolovou GOC
  • CONCLUSIONS: Increase serum TGs, UA and GL concentrations were higher in the middle-aged individuals compared with their children in families independently of their lifespan. The serum adiponectin concentration was the highest in the oldest old individuals implying beneficial influence on lifespan. Independently of family's lifespan history, the youngest individuals with CETPB2B2 genotype, compared with individuals with CETPB1B1 genotypes, had lower serum CETP concentrations. The knowledge of the unfavourable gene(s)influencing human lifespan may be helpful in encouraging individuals to follow healthier lifestyle habits and better control their high-risk biomarkers.
  • Reduction of Vascular Inflammation, LDL-C, or Both for the Protection from Cardiovascular Events? [Review]
    Open Cardiovasc Med J. 2018; 12:29-40.Reklou A, Doumas M, … Athyros VGOC
  • CONCLUSIONS: Both LDL-C and inflammation reduction are beneficial to the reduction of CVD risk. However, canakinumab is a very expensive drug that only induced a 15% reduction in CVD events, thus drastically reducing the possibility for it to be used in clinical practice. Besides, canakinumab is associated with increased infections, some fatal. A potent statin with anti-inflammatory effects is probably the best choice for the majority of those needing hypolipidaemic drug therapy.
  • A Very Rare Cause of Lower Limb Ischemia in Young People: Popliteal Artery Entrapment. [Journal Article]
    Open Cardiovasc Med J. 2018; 12:18-28.Altinsoy HB, Alatas O, … Dogan OFOC
  • CONCLUSIONS: PAES can result in lower limb ischemia due to chronic vascular trauma in young healthy patients. The use of diagnostic tools such as US, a non-invasive method, and MRA are effective diagnostic tools for early diagnosis. With their combined approach, exact and early diagnosis can be achieved. PA release, alone or with arterial bypass using RA, is a viable treatment option when intervention is necessary to prevent limb loss in the early stages of the disease.
  • A Practical Approach to the Percutaneous Treatment of Iatrogenic Aorto-coronary Dissection. [Case Reports]
    Open Cardiovasc Med J. 2018; 12:50-54.Kassimis G, Raina TOC
  • Catheter-induced aortic dissection during coronary angiography and Percutaneous Coronary Intervention (PCI) is a relatively infrequent, but potentially life-threatening complication. Patients who suffer this complication may require emergency aortic surgery. More recently, reports of treating the ostium of the dissected coronary artery have emerged as an alternative therapeutic option. In this ar…