- Obesity Paradox and Non-Arteritic Anterior Ischemic Optic Neuropathy Risk. [Journal Article]Ophthalmology. 2026 Oct 31. [Online ahead of print]O
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- Re: Battista et al.: Late-Onset Leber Hereditary Optic Neuropathy: Disease Triggers and Prognostic Factors in a Large Italian Cohort. [Letter]Ophthalmology. 2026 Oct 30. [Online ahead of print]O
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- Targetoid Maculopathy in CEP290-Related Joubert Syndrome. [Journal Article]Ophthalmology. 2026 Oct 30. [Online ahead of print]O
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- Re: Abdi et al.: Systemic Interleukin-6 Inhibition and Risk of Diabetic Retinopathy Development and Progression (Ophthalmology. 2026). [Letter]Ophthalmology. 2026 Oct 31. [Online ahead of print]O
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- Comparison of clinical outcomes after 25-gauge vitrectomy with and without uncomplicated cataract surgery for idiopathic epiretinal membrane. [Journal Article]BMC Ophthalmol. 2026 Aug 04; 26(1).BO
- CONCLUSIONS: Combined vitrectomy with uncomplicated cataract surgery may potentially be as effective as vitrectomy alone with respect to metamorphopsia and anatomical outcomes for IERM patients. However, the BCVA recovery was better in the Combined group.
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- Risk-Stratified Outcomes of Prophylactic Laser Versus Observation for Pediatric Peripheral Retinal Lesions. [Journal Article]Ophthalmol Retina. 2026 Oct 30. [Online ahead of print]OR
- CONCLUSIONS: Prophylactic laser retinopexy in pediatric eyes was preferentially applied to lesions with greater anatomic and clinical risk but was not associated with a statistically significant reduction in retinal detachment rates compared with observation. These findings suggest that many pediatric peripheral retinal lesions may be safely managed with observation and highlight the need for pediatric-specific evidence to guide treatment decisions.
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- Ciliochoroidal Leiomyoma Mimicking Uveal Melanoma. [Journal Article]Ophthalmology. 2026 Oct 30. [Online ahead of print]O
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- Early outcomes of switching from bevacizumab to aflibercept-jbvf in exudative macular diseases: a real-world study. [Journal Article]
- CONCLUSIONS: Administration of aflibercept-jbvf following three monthly bevacizumab injections was temporally associated with a statistically significant but modest very early reduction in CST at 4 weeks in this heterogeneous cohort of exudative macular diseases. Because DME, neovascular AMD-related MNV, and RVO represent biologically and clinically distinct disease entities, the pooled findings should be interpreted as descriptive cohort-level estimates within this shared treatment pathway rather than as evidence of a uniform treatment effect across these conditions. A small numerical trend toward BCVA improvement was observed, but the change was not statistically significant in either the unadjusted or GEE-adjusted analysis. Because this was a single-arm study without a comparator group, the observed anatomical change cannot be attributed specifically to aflibercept-jbvf and may partly reflect a delayed or cumulative response to prior bevacizumab, regression to the mean, or natural variability in retinal thickness. Diagnosis-specific findings were exploratory, and the 4-week endpoint does not provide information regarding durability of response or longer-term treatment burden.
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- Time to diabetic retinopathy and its prognostic factors among adults with type 2 diabetes mellitus in Johor, Malaysia from 2015 to 2019: a retrospective cohort study using surveillance data. [Journal Article]
- CONCLUSIONS: Diabetic retinopathy develops within a relatively short duration following type 2 diabetes mellitus diagnosis and is influenced by a combination of metabolic, clinical, and complication-related factors. Early risk stratification and integrated management of modifiable risk factors are essential to delay the onset of diabetic retinopathy. These findings provide important real-world evidence to support targeted screening and public health strategies in Malaysia.
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- Different vault outcomes following implantable collamer lens implantation in eyes with ciliary body cysts: a case report. [Case Reports]
- CONCLUSIONS: These two cases suggest that cyst morphology may be one of several factors associated with postoperative ICL vault in eyes with sulcus-involved ciliary body cysts. Detailed preoperative UBM assessment of cyst structure and sulcus anatomy may be useful for individualized surgical planning and postoperative follow-up. Larger studies are warranted to determine whether specific morphologic characteristics of ciliary body cysts are associated with postoperative ICL haptic behavior and vault outcomes.
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- Congenital fibrovascular pupillary membrane with secondary glaucoma and associated fundus anomalies: a case report and literature review. [Case Reports]
- CONCLUSIONS: We report a clinically rare case of CFPM-induced secondary glaucoma, with concurrent fundus anomalies. Comprehensive ophthalmic evaluation is essential for CFPM patients, with attention to the possibility of posterior segment involvement. For severe cases, timely surgical intervention is recommended to preserve intraocular anatomical structures, with emphasis on long-term postoperative follow-up and the management of complications.
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- Is blepharoplasty more than a cosmetic procedure? Quantitative analysis of cutaneous changes in eyelid skin and clinical effects in elderly patients with dermatochalasis. [Journal Article]
- CONCLUSIONS: The present study observed quantifiable alterations in pretarsal eyelid skin bioimpedance indices alongside symptomatic and ocular surface improvements following functional blepharoplasty in elderly patients with dermatochalasis and concurrent refractory blepharitis. Beyond its established functional benefits for visual field restoration, the alleviation of anatomical skin redundancy may favorably alter the local eyelid microenvironment. The observed reductions in pretarsal skin lipid and moisture indices provide a preliminary basis for the hypothesis that surgical debulking could indirectly influence microbial or parasitic colonization, such as Demodex mites, and bacterial lipase activity. However, these proposed biological mechanisms remain hypothetical and require future validation through prospective studies incorporating direct microbiological and acarological quantification.
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- Myopia prevalence among students in nine-year and independent compulsory education schools: a retrospective cross-sectional study. [Journal Article]
- CONCLUSIONS: The prevalence of myopia was relatively high and surged from low-grade to high-grade levels among compulsory students in the Nanshan district. An association between the educational transition model and myopia prevalence was observed. However, this association was exploratory, because the educational transition exposure is fully confounded with school identity. Further longitudinal studies with multiple schools across diverse regions are warranted to clarify the specific mechanisms through which educational structure influences ocular health.
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- Diagnostic value of tear Galectin-1 and Galectin-3 in keratoconus: a prospective case-control study. [Journal Article]
- CONCLUSIONS: Tear Galectin-1 and Galectin-3 levels were significantly elevated in patients with keratoconus compared with healthy controls. Among the two galectins, Galectin-3 demonstrated superior diagnostic performance, supporting further investigation of Galectin-3 as a potential biomarker for keratoconus.
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- Contractile morning glory disc anomaly associated with total retinal detachment: a case report. [Case Reports]
- CONCLUSIONS: Contractile morning glory disc anomaly is a rare developmental optic nerve head disorder with distinctive dynamic features. Dynamic imaging provides valuable visualization of the contractile behavior of the malformed optic disc and may assist in diagnosis and risk assessment. Retinal detachment and associated vascular abnormalities may occur in these patients, although their underlying mechanisms require further investigation.
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