(PLoS Med[TA])
5,365 results
  • Risk stratification for significant acute traumatic intracranial hemorrhage in older adults after a ground-level fall: A prospective multicentre cohort study. [Multicenter Study]
    PLoS Med. 2026 Aug; 23(8):e1004935.Dubucs X, Even C, … Émond MPM
  • CONCLUSIONS: Our findings revealed that factors drawn from patient history and physical examination were associated with significant acute traumatic intracranial hemorrhage in older adults after a ground-level fall. Incorporating these factors into decision rules could provide a reliable strategy to stratify risk and reduce unnecessary CT scan. We hypothesize that the PIWI 1 rule could be used in patients with a clear history of the fall, while the PIWI 2 rule could be applied in other cases. Such rules need to be validated externally and independently for their implementation in clinical practice, but may already be of aid for identifying high-risk patients.
  • Expanding the Developmental Origins of Health and Disease beyond maternal behaviors. [Journal Article]
    PLoS Med. 2026 Jul; 23(7):e1005208.Lee AR, Hawcutt DB, … Sinha IPPM
  • Developmental Origins of Health and Disease (DOHaD) research has long emphasized maternal pregnancy behaviors as key determinants of child health. New evidence recently published in PLOS Medicine suggests the greatest opportunities to improve child health may lie in tackling socioeconomic disadvantage rather than maternal behavior alone.
  • Maternal congenital heart disease: Implications for the next generation. [Review]
    PLoS Med. 2026 Jul; 23(7):e1005191.Leirgul E, Greve GPM
  • Advances in medical and surgical treatment of congenital heart disease (CHD) now allows most affected individuals to reach adulthood and parenthood. While maternal CHD is associated with pregnancy complications, emerging evidence suggests a possible increased risk of developmental challenges in offspring, particularly among children of mothers with severe CHD.
  • The cancer survivorship paradox in the digital era. [Journal Article]
    PLoS Med. 2026 Jul; 23(7):e1005174.Hegarty J, Toygar I, … Pawlowska EPM
  • Many assumptions around patient needs and support guide current oncology practice and cancer survivorship care in the digital era. Addressing these assumptions and providing smarter, holistic, tech-enabled follow-up models are essential for truly effective and sustainable person-centered care.
  • Exploring parental prenatal influences on child health: A multicohort study and data visualisation tool. [Journal Article]
    PLoS Med. 2026 Jul; 23(7):e1005153.Sharp GC, Lawlor DA, … Relton CLPM
  • CONCLUSIONS: Our findings suggest that wider familial socioeconomic conditions may be a more important determinant of child health than specific parental health behaviours prenatally. Interventions to improve population health may be most effective if they target wider social inequalities, rather than individual behaviours and mothers specifically. We encourage researchers to use EPoCH Explorer to prioritise associations for exploration in their own datasets, thus enabling replication and cross-context comparison to validate and extend the generalisability of our findings.
  • Whose fears count? Legitimacy, trust and viral outbreak responses after COVID-19. [Editorial]
    PLoS Med. 2026 Jul; 23(7):e1005184.Grais RFPM
  • COVID-19 transformed viral outbreak response from a predominantly public health challenge into a political and security concern. Recent responses to Ebola, mpox, and other emerging infections suggest that preparedness is increasingly shaped by whose fears are prioritized in decision-making. The challenge is ensuring that competing perceptions of risk are managed in ways that are perceived as legi…