- Severe akathisia as a side effect of metoclopramide. [Case Reports]
- CONCLUSIONS: Movement disorders as an adverse effect of metoclopramide have been described on a regular basis over the past decades. Case reports such as this confirm there is under-recognition of adverse effects and emphasize the need to take a comprehensive medication history and recognize well known side effects of medications such as metoclopramide.
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- Introduction of pharmaceutical expertise in a palliative care team in Sweden. [Journal Article]
- CONCLUSIONS: The principal result of this project is that inclusion of pharmaceutical expertise on a palliative care team can be a valuable asset for the team in pharmaceutical issues and of great benefit for stock management, including cost savings and improvement of drug logistics.
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- Cost reduction associated with restriction policy on dispensing intravenous esomeprazole in Lebanon. [Journal Article]
- CONCLUSIONS: Even though the clinical role of pharmacy practice in Middle Eastern countries is limited, this study highlighted the impact of the pharmacist on cost through the implementation of restriction policy during dispensing procedure, leading to a cost reduction by four folds.
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- Azathioprine-induced severe cholestatic hepatitis in patient carrying TPMT*3C polymorphism. [Case Reports]
- CONCLUSIONS: Although, hematotoxicity seems to be associated with homozygous TPMT variants, a possible association between azathioprine hepatotoxicity and a TPMT*3C genotype should be investigated further.
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- Evaluation of three brands of drug interaction software for use in intensive care units. [Journal Article]
- CONCLUSIONS: The DR and LI programs displayed appropriate sensitivity and specificity for identifying drug-drug interactions of interest in intensive care units. Drug interaction software programs help pharmacists and health care teams in the prevention and recognition of drug-drug interactions and optimize safety and quality of care delivered in intensive care units.
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- Diagnosing infections: a qualitative view on prescription decisions in general practice over time. [Journal Article]
- CONCLUSIONS: Large variability and individuality characterized the GPs' diagnostic procedures, contrasted by consistency through time. If modification of diagnostic routines is needed, provision of "scientific facts" and technological aids is insufficient. A prerequisite for changing practice is GPs' acceptance of accuracy of information and of reliability, applicability, and relevance of technology, for physician and/or patient.
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- Generic and therapeutic substitutions: are they always ethical in their own terms? [Review]
- Cost containment-driven drug substitution, whether generic or therapeutic, is defined as switching to another drug because it is cheaper. So far, such substitutions have drawn their public legitimacy from the general belief that they would not compromise the clinical interests of patients and certainly not violate their right to decline them if they did. This article does not enter the debate on …
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- "Patients don't lie"; a view on adherence in asthma. [Controlled Clinical Trial]
- CONCLUSIONS: This illustrates that at least 43.9% of the participants in the trial dared to report nonadherence to asthma medication.
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- Which factors predict the time spent answering queries to a drug information centre? [Randomized Controlled Trial]
- CONCLUSIONS: The most important workload factor predicting the time spent handling the queries in this study was the type of literature search that had to be performed. The categorisation of queries as judgmental or not, also affected the time spent answering the queries. The number of drugs involved did not significantly influence the time spent answering drug information queries.
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- The incidence of potential drug-drug interactions in elderly patients with arterial hypertension. [Journal Article]
- CONCLUSIONS: Drug-drug interactions are common in elderly hypertensive patients. Computer-based screening could help pharmacists and physicians to recognize potential, clinically significant interactions.
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- Antiretroviral adherence program in HIV patients: a feasibility study in the Swiss HIV Cohort Study. [Multicenter Study]
- CONCLUSIONS: The encountered difficulties rely on the implementation, i.e., on the program and the health care system levels rather than on the patient level. Implementation needs to be evaluated further; to be feasible a new adherence program needs to fit into the daily routine of the centre and has to be supported by all trained healthcare providers. However, this study shows that patients' adherence behavior evolved differently in both groups; it decreased more quickly over time in the control than in the intervention group. RCTs are eventually needed to assess the clinical impact of such an adherence program and to verify whether skilled pharmacists can ensure continuity of care for HIV outpatients.
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- Opinion comparison concerning future information technology in Finnish community pharmacies. [Journal Article]
- CONCLUSIONS: The managers and staff pharmacists have different views of the importance of IT features, reflecting their different professional duties in the community pharmacy. A high priority was given for the features familiar to the users and needed in their daily practice. This indicates the need for involving different occupation groups in planning the new IT systems for community pharmacies.
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- Pharmacy education in Cuba. [Review]
- CONCLUSIONS: All University Schools of Pharmacy are formally involved in the continuing professional development of practitioners as an important part of the educational life cycle for pharmacists.
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- Soon: a new year, a new name, a new face. [Editorial]Pharm World Sci. 2010 Oct; 32(5):545.PW
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- Structure and procedures of the pharmacy and therapeutic committees in Spanish hospitals. [Multicenter Study]
- CONCLUSIONS: Spanish P&T Committees have a similar structure and function, a multi-disciplinary professional composition to carry out an important assessment activity. This activity is higher in large hospitals and in university hospitals. The proportion of the approved and rejected drugs is similar in different types of hospital. The Therapeutic Interchange Guidelines, the use of application models and the reports follow the indications of scientific collaborative groups, thus being used more in Spain than in other countries.
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